{"formatVersion":"1.1","id":"https://www.mentalhealth.com/library/autism-and-premature-death","path":"/library/autism-and-premature-death","url":"https://www.mentalhealth.com/library/autism-and-premature-death","title":"Autism Spectrum Disorder and Premature Death","family":"Library detail","description":"Explore the health risks associated with autism and how early interventions, comprehensive care, and supportive strategies can improve outcomes.","language":"en-US","access":{"audience":"public","indexable":true},"provenance":{"sourceUrl":"https://www.mentalhealth.com/library/autism-and-premature-death","wordpressId":"471","contentCompleteness":"complete","dateScope":"original-source"},"authors":[{"@type":"Person","@id":"https://www.mentalhealth.com/people/briana-casali#person","name":"Briana Casali, Ph.D.","url":"https://www.mentalhealth.com/people/briana-casali"}],"reviewer":{"@type":"Person","@id":"https://www.mentalhealth.com/people/shivani-kharod#person","name":"Shivani Kharod, Ph.D.","url":"https://www.mentalhealth.com/people/shivani-kharod"},"dates":{"datePublished":"2025-06-06T10:29:04Z","dateModified":"2026-05-12T12:11:54Z","lastReviewed":"2025-06-06"},"content":{"html":"

Autism Spectrum Disorder and Premature Death

Written by \"\"Briana Casali, Ph.D.Medically reviewed by \"\"Shivani Kharod, Ph.D.

Published on · Updated on

Content note: Some readers may find parts of this discussion sensitive.

The link between autism spectrum disorder (ASD) and premature death can present people with a range of health challenges that deserve thoughtful attention and proactive support. Some people with ASD may have an increased risk of epilepsy, mental health difficulties, and other medical conditions that can affect their overall well-being and lifespan.

These health concerns often depend on factors like early diagnosis and consistent access to healthcare. With the appropriate care and support, people with autism can improve their health outcomes and enjoy longer lives while managing the challenges associated with ASD.

\"A

Key takeaways

  • Some autistic people face health complications associated with increased risk of premature death, but outcomes vary widely.
  • Epilepsy, mental health difficulties, sleep problems, and other co-occurring conditions can create additional care needs.
  • Individualized healthcare, early support, preventive monitoring, and caregiver resources can help address these risks.

The Connection Between ASD and Premature Death

Understanding health outcomes in autism is essential for patients and their families or caregivers, as it can help guide more effective care strategies. Studies suggest that people with autism spectrum disorder may face a higher likelihood of certain health complications that could affect lifespan⁠[1].

However, these statistics reflect opportunities for improvement rather than predetermined outcomes. Additionally, it’s worth noting that Western medicine and functional medicine approach autism from different perspectives. Aligning care with one’s beliefs and attitude is an important part of treating autism.

The impact of autism spectrum disorder on health varies significantly among different people, with timely diagnosis and consistent care playing major roles in overall well-being.

In one particular study, researchers found that “people with ASD had substantially elevated mortality rates and died on average 16 years earlier than expected,” but they also emphasized that many of these deaths could have been preventable⁠[1]. Many people with autism live long, healthy lives when they receive appropriate support and medical attention.

There are also some limitations that should be acknowledged regarding premature death rates, including small sample sizes, varying diagnostic criteria across different time periods, and differences in healthcare access that can skew results.

Outcomes may differ significantly from population-level statistics, emphasizing the importance of personalized care approaches. To provide that kind of personalized care, it’s essential to understand which health issues most commonly affect people with ASD.

Key Health Considerations for People with ASD

Several health factors require special attention in people with autism; however, epilepsy is one of the most significant concerns. Epilepsy affects approximately 20-40% of people with autism, particularly those with more severe symptoms or learning difficulties⁠[2]. This connection appears to be related to genetic variations, brain chemistry differences, and environmental factors that influence both conditions.

Lifespan risks rise significantly when autism and epilepsy occur together, as research shows this combination can significantly increase health risks⁠[3]. However, early identification and proper seizure management can dramatically improve outcomes. For example, many seizure-related complications are preventable through education, lifestyle changes, and appropriate medication management.

Therefore, regular seizure monitoring and comprehensive epilepsy care for people with autism are important for maintaining overall health. Seizure risks can be reduced with proper treatment and family education, improving safety and quality of life. While epilepsy is one of the most pressing concerns, mental health conditions also play a significant role in long-term outcomes.

Mental Health Factors and ASD

Mental health plays a significant role in the overall well-being of people with autism. Autism and mental health challenges often intersect in ways that require specialized understanding and support approaches. For example, people with autism face higher rates of depression, anxiety, and other mental health conditions compared to the general population⁠[4].

Social challenges and communication differences that sometimes come with ASD can make it harder for people to express their feelings or seek help when experiencing mental health difficulties. This communication barrier means that family members, caregivers, and healthcare providers need to be especially attentive to signs of emotional distress or changes in behavior patterns.

Evidence indicates that even autistic people without learning disabilities still face particular mental health risks, including increased rates of thoughts about self-harm⁠[4]. Mental health therapy tailored for neurodivergent people and strong, understanding support networks significantly reduce these risks. 

For people with high-functioning autism, health considerations may focus more on mental health support and stress management. The key to addressing mental health concerns is creating environments where people with autism feel understood, valued, and supported.

Medical Comorbidities for People with ASD

People with autism often experience additional medical conditions that require ongoing attention and management. These comorbidities include various genetic disorders, neurological conditions, and physical health issues that can affect overall well-being and life expectancy⁠[4].

Common Associated Conditions

Common genetic conditions associated with autism include Down syndrome, Fragile X syndrome, and tuberous sclerosis complex. Neurological conditions such as cerebral palsy, migraines, and hydrocephalus also occur more frequently in people with autism⁠[5]. Understanding these connections helps healthcare providers develop comprehensive care plans that address multiple health needs simultaneously.

Physical health considerations for people with ASD often include:

    \n
  • Gastrointestinal issues
    • \n
  • Sleep disorders
    • \n
  • Sensory processing differences
    • \n
  • Cardiovascular health concerns
    • \n
  • Immune system variations
    • \n

Regular medical monitoring and preventive care become especially important for addressing these conditions early and maintaining optimal health throughout life. As people with autism grow older, managing multiple health conditions can become more complex. Understanding autism development in later life helps families and providers plan ahead for evolving care needs.

Preventing Premature Death in People with ASD

Support for autistic people should reflect their individual strengths, communication preferences, and health needs. Services may include psychological, educational, occupational, or speech-language support, alongside treatment for co-occurring symptoms and conditions⁠[6].

Healthcare providers recommend regular screening for common comorbidities, including epilepsy monitoring, mental health assessments, and physical health checkups tailored to autism-related needs. Strategies that support health for people with ASD include:

    \n
  • Structured environments: Families can create predictable routines and spaces that reduce stress and anxiety levels for better overall health.
    • \n
  • Communication development: Healthcare teams should build clear methods for expressing health concerns and symptoms that work for each person's abilities.
    • \n
  • Healthcare relationships: People with autism benefit from establishing strong connections with providers who understand autism and can provide specialized care.
    • \n
  • Family education: Caregivers need training to recognize warning signs and know when to seek immediate medical attention.
    • \n
  • Care coordination: Families should work with professionals who help navigate complex medical needs and ensure comprehensive treatment approaches.
    • \n

As people with autism grow older, their needs may shift in ways that require new approaches to care and support. Additionally, staying informed about rising autism rates and improved diagnostic practices helps families access better resources. 

Impact on Families and Caregivers

When someone has autism and faces additional health challenges, the whole family feels the impact. Parents often experience high levels of stress and worry as they coordinate care between different doctors, manage medications, and watch for new health problems.

This constant vigilance takes an emotional toll on families, while the financial burden of multiple specialists, treatments, and time away from work can add another layer of stress. Many families find themselves stretched thin trying to provide the best possible care while maintaining their own stability and relationships.

Caregivers also frequently put their health and well-being on the back burner while focusing on their loved one’s complex needs. This can lead to burnout, depression, and physical health problems that make it harder to provide good care. Brothers and sisters also sometimes feel forgotten or scared about their sibling’s health issues.

The good news is that families do better when they get proper support, whether that’s education about the conditions, respite care to take breaks, counseling to process emotions, or connections with other families going through similar experiences. Everyone benefits when the whole family stays strong and supported, including the person with autism.

Subject matter expert

\"\"

Holly Schiff Psy.D.

Children, adolescents, and families

Building a Brighter Future

The future holds tremendous promise for improving outcomes and quality of life for people with autism. Advances in medical care, increased awareness among healthcare providers, and a growing understanding of autism contribute to better support and longer, healthier lives for autistic people. Modern approaches emphasize personalized care that recognizes each person's unique health needs.

Early intervention, comprehensive care, and ongoing support remain the most powerful tools for ensuring that people with autism live full and meaningful lives surrounded by people who understand and value their unique perspectives and contributions. With continued research and strong support systems, people with autism can look forward to bright futures while managing their unique health considerations.

References

  1. Hirvikoski, T., Mittendorfer-Rutz, E., Boman, M., Larsson, H., Lichtenstein, P., & Bölte, S. (2016). Premature mortality in autism spectrum disorder. British Journal of Psychiatry, 208(3), 232-238. Cambridge University Press. Accessed October 10 2026.
  2. Hawkes, N. (2016). People with autism die 16 years earlier on average, says charity. BMJ, i1615. BMJ. Accessed October 10 2026.
  3. Mortality rate is increased in persons with autism who also have epilepsy, study finds. (2011, April 11). ScienceDaily. sciencedaily.com. Accessed October 10 2026.
  4. Suicide and Autism. (2020, July 14). Autistica. autistica.org.uk. Accessed October 10 2026.
  5. Al-Beltagi, M. (2021). Autism medical comorbidities. World Journal of Clinical Pediatrics, 10(3), 15-28. wjgnet.com. Accessed October 10 2026.
  6. National Institute of Mental Health. (2025). Autism Spectrum Disorder. National Institutes of Health. National Institute of Mental Health. Accessed October 10 2026.

Medical Content

The Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy.

About MentalHealth.com

MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.

\"\"

Author

Briana Casali, Ph.D.

Writer, Editor

Briana Casali, Ph.D. is an experienced editor and professional writer with a background in academic editing and journalism for high-growth organizations.

Published
Updated
\"\"

Medical Reviewer

Shivani Kharod, Ph.D.

Ph.D.

Shivani Kharod, Ph.D. is a medical reviewer with over 10 years of experience in delivering scientifically accurate health content.

Reviewed
\"\"

Related community

Autism Spectrum Disorder

A space for perspectives on autistic experiences, connection, and support across life stages.

","text":"Home Library Autism Spectrum Disorder Autism Spectrum Disorder and Premature Death Autism Spectrum Disorder and Premature Death Written by Briana Casali, Ph.D.Medically reviewed by Shivani Kharod, Ph.D. Published on June 6, 2025 · Updated on May 12, 2026 Content note: Some readers may find parts of this discussion sensitive. The link between autism spectrum disorder (ASD) and premature death can present people with a range of health challenges that deserve thoughtful attention and proactive support. Some people with ASD may have an increased risk of epilepsy, mental health difficulties, and other medical conditions that can affect their overall well-being and lifespan. These health concerns often depend on factors like early diagnosis and consistent access to healthcare. With the appropriate care and support, people with autism can improve their health outcomes and enjoy longer lives while managing the challenges associated with ASD. Key takeaways Some autistic people face health complications associated with increased risk of premature death, but outcomes vary widely. Epilepsy, mental health difficulties, sleep problems, and other co-occurring conditions can create additional care needs. Individualized healthcare, early support, preventive monitoring, and caregiver resources can help address these risks. The Connection Between ASD and Premature Death Understanding health outcomes in autism is essential for patients and their families or caregivers, as it can help guide more effective care strategies. Studies suggest that people with autism spectrum disorder may face a higher likelihood of certain health complications that could affect lifespan⁠[1]. However, these statistics reflect opportunities for improvement rather than predetermined outcomes. Additionally, it’s worth noting that Western medicine and functional medicine approach autism from different perspectives. Aligning care with one’s beliefs and attitude is an important part of treating autism. The impact of autism spectrum disorder on health varies significantly among different people, with timely diagnosis and consistent care playing major roles in overall well-being. In one particular study, researchers found that “people with ASD had substantially elevated mortality rates and died on average 16 years earlier than expected,” but they also emphasized that many of these deaths could have been preventable⁠[1]. Many people with autism live long, healthy lives when they receive appropriate support and medical attention. There are also some limitations that should be acknowledged regarding premature death rates, including small sample sizes, varying diagnostic criteria across different time periods, and differences in healthcare access that can skew results. Outcomes may differ significantly from population-level statistics, emphasizing the importance of personalized care approaches. To provide that kind of personalized care, it’s essential to understand which health issues most commonly affect people with ASD. Key Health Considerations for People with ASD Several health factors require special attention in people with autism; however, epilepsy is one of the most significant concerns. Epilepsy affects approximately 20-40% of people with autism, particularly those with more severe symptoms or learning difficulties⁠[2]. This connection appears to be related to genetic variations, brain chemistry differences, and environmental factors that influence both conditions. Lifespan risks rise significantly when autism and epilepsy occur together, as research shows this combination can significantly increase health risks⁠[3]. However, early identification and proper seizure management can dramatically improve outcomes. For example, many seizure-related complications are preventable through education, lifestyle changes, and appropriate medication management. Therefore, regular seizure monitoring and comprehensive epilepsy care for people with autism are important for maintaining overall health. Seizure risks can be reduced with proper treatment and family education, improving safety and quality of life. While epilepsy is one of the most pressing concerns, mental health conditions also play a significant role in long-term outcomes. Mental Health Factors and ASD Mental health plays a significant role in the overall well-being of people with autism. Autism and mental health challenges often intersect in ways that require specialized understanding and support approaches. For example, people with autism face higher rates of depression, anxiety, and other mental health conditions compared to the general population⁠[4]. Social challenges and communication differences that sometimes come with ASD can make it harder for people to express their feelings or seek help when experiencing mental health difficulties. This communication barrier means that family members, caregivers, and healthcare providers need to be especially attentive to signs of emotional distress or changes in behavior patterns. Evidence indicates that even autistic people without learning disabilities still face particular mental health risks, including increased rates of thoughts about self-harm⁠[4]. Mental health therapy tailored for neurodivergent people and strong, understanding support networks significantly reduce these risks. For people with high-functioning autism, health considerations may focus more on mental health support and stress management. The key to addressing mental health concerns is creating environments where people with autism feel understood, valued, and supported. Medical Comorbidities for People with ASD People with autism often experience additional medical conditions that require ongoing attention and management. These comorbidities include various genetic disorders, neurological conditions, and physical health issues that can affect overall well-being and life expectancy⁠[4]. Common Associated Conditions Common genetic conditions associated with autism include Down syndrome, Fragile X syndrome, and tuberous sclerosis complex. Neurological conditions such as cerebral palsy, migraines, and hydrocephalus also occur more frequently in people with autism⁠[5]. Understanding these connections helps healthcare providers develop comprehensive care plans that address multiple health needs simultaneously. Physical health considerations for people with ASD often include: Gastrointestinal issues Sleep disorders Sensory processing differences Cardiovascular health concerns Immune system variations Regular medical monitoring and preventive care become especially important for addressing these conditions early and maintaining optimal health throughout life. As people with autism grow older, managing multiple health conditions can become more complex. Understanding autism development in later life helps families and providers plan ahead for evolving care needs. Preventing Premature Death in People with ASD Support for autistic people should reflect their individual strengths, communication preferences, and health needs. Services may include psychological, educational, occupational, or speech-language support, alongside treatment for co-occurring symptoms and conditions⁠[6]. Healthcare providers recommend regular screening for common comorbidities, including epilepsy monitoring, mental health assessments, and physical health checkups tailored to autism-related needs. Strategies that support health for people with ASD include: Structured environments: Families can create predictable routines and spaces that reduce stress and anxiety levels for better overall health. Communication development: Healthcare teams should build clear methods for expressing health concerns and symptoms that work for each person's abilities. Healthcare relationships: People with autism benefit from establishing strong connections with providers who understand autism and can provide specialized care. Family education: Caregivers need training to recognize warning signs and know when to seek immediate medical attention. Care coordination: Families should work with professionals who help navigate complex medical needs and ensure comprehensive treatment approaches. As people with autism grow older, their needs may shift in ways that require new approaches to care and support. Additionally, staying informed about rising autism rates and improved diagnostic practices helps families access better resources. Impact on Families and Caregivers When someone has autism and faces additional health challenges, the whole family feels the impact. Parents often experience high levels of stress and worry as they coordinate care between different doctors, manage medications, and watch for new health problems. This constant vigilance takes an emotional toll on families, while the financial burden of multiple specialists, treatments, and time away from work can add another layer of stress. Many families find themselves stretched thin trying to provide the best possible care while maintaining their own stability and relationships. Caregivers also frequently put their health and well-being on the back burner while focusing on their loved one’s complex needs. This can lead to burnout, depression, and physical health problems that make it harder to provide good care. Brothers and sisters also sometimes feel forgotten or scared about their sibling’s health issues. The good news is that families do better when they get proper support, whether that’s education about the conditions, respite care to take breaks, counseling to process emotions, or connections with other families going through similar experiences. Everyone benefits when the whole family stays strong and supported, including the person with autism. Subject matter expert Holly Schiff Psy.D. Children, adolescents, and families Building a Brighter Future The future holds tremendous promise for improving outcomes and quality of life for people with autism. Advances in medical care, increased awareness among healthcare providers, and a growing understanding of autism contribute to better support and longer, healthier lives for autistic people. Modern approaches emphasize personalized care that recognizes each person's unique health needs. Early intervention, comprehensive care, and ongoing support remain the most powerful tools for ensuring that people with autism live full and meaningful lives surrounded by people who understand and value their unique perspectives and contributions. With continued research and strong support systems, people with autism can look forward to bright futures while managing their unique health considerations. References Hirvikoski, T., Mittendorfer-Rutz, E., Boman, M., Larsson, H., Lichtenstein, P., & Bölte, S. (2016). Premature mortality in autism spectrum disorder. British Journal of Psychiatry, 208(3), 232-238. Cambridge University Press. Accessed October 10 2026. Hawkes, N. (2016). People with autism die 16 years earlier on average, says charity. BMJ, i1615. BMJ. Accessed October 10 2026. Mortality rate is increased in persons with autism who also have epilepsy, study finds. (2011, April 11). ScienceDaily. sciencedaily.com. Accessed October 10 2026. Suicide and Autism. (2020, July 14). Autistica. autistica.org.uk. Accessed October 10 2026. Al-Beltagi, M. (2021). Autism medical comorbidities. World Journal of Clinical Pediatrics, 10(3), 15-28. wjgnet.com. Accessed October 10 2026. National Institute of Mental Health. (2025). Autism Spectrum Disorder. National Institutes of Health. National Institute of Mental Health. Accessed October 10 2026. Medical Content The Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy. About MentalHealth.com MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life. Author Briana Casali, Ph.D. Writer, Editor Briana Casali, Ph.D. is an experienced editor and professional writer with a background in academic editing and journalism for high-growth organizations. Published June 6, 2025 Updated May 12, 2026 Medical Reviewer Shivani Kharod, Ph.D. Ph.D. Shivani Kharod, Ph.D. is a medical reviewer with over 10 years of experience in delivering scientifically accurate health content. Reviewed June 6, 2025 Related community Autism Spectrum Disorder A space for perspectives on autistic experiences, connection, and support across life stages. Table of contentsChoose a section The Connection Between ASD and Premature Death Key Health Considerations for People with ASD Mental Health Factors and ASD Medical Comorbidities for People with ASD Preventing Premature Death in People with ASD Impact on Families and Caregivers Building a Brighter Future View more","wordCount":1809},"schema":{"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://www.mentalhealth.com/#organization","name":"MentalHealth.com","url":"https://www.mentalhealth.com/","publishingPrinciples":"https://www.mentalhealth.com/publishing/editorial-policy"},{"@type":"WebSite","@id":"https://www.mentalhealth.com/#website","url":"https://www.mentalhealth.com/","name":"MentalHealth.com","inLanguage":"en-US","publisher":{"@id":"https://www.mentalhealth.com/#organization"}},{"@type":"BreadcrumbList","@id":"https://www.mentalhealth.com/library/autism-and-premature-death#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.mentalhealth.com/"},{"@type":"ListItem","position":2,"name":"Library","item":"https://www.mentalhealth.com/library"},{"@type":"ListItem","position":3,"name":"Autism Spectrum Disorder","item":"https://www.mentalhealth.com/library/autism-spectrum-disorder"},{"@type":"ListItem","position":4,"name":"Autism Spectrum Disorder and Premature Death","item":"https://www.mentalhealth.com/library/autism-and-premature-death"}]},{"@type":"ImageObject","@id":"https://www.mentalhealth.com/library/autism-and-premature-death#primaryimage","url":"https://www.mentalhealth.com/assets/optimized/34e31fd41ee12b97324c289e.webp","contentUrl":"https://www.mentalhealth.com/assets/optimized/34e31fd41ee12b97324c289e.webp","width":1200,"height":800,"encodingFormat":"image/webp","caption":"A parent helps a child with an activity at a table outdoors."},{"@type":"Person","@id":"https://www.mentalhealth.com/people/briana-casali#person","name":"Briana Casali, Ph.D.","url":"https://www.mentalhealth.com/people/briana-casali","jobTitle":"Writer, Editor","image":"https://www.mentalhealth.com/assets/optimized/253d8732b3a859574aaa5481.jpg","memberOf":[{"@id":"https://www.mentalhealth.com/publishing#department"}]},{"@type":"Person","@id":"https://www.mentalhealth.com/people/shivani-kharod#person","name":"Shivani Kharod, Ph.D.","url":"https://www.mentalhealth.com/people/shivani-kharod","jobTitle":"Ph.D.","image":"https://www.mentalhealth.com/assets/optimized/d298e1ab0221c766e22a9fce.jpg","sameAs":["https://www.linkedin.com/in/shivanikharod"],"memberOf":[{"@id":"https://www.mentalhealth.com/clinical-affairs#department"}]},{"@type":"Article","@id":"https://www.mentalhealth.com/library/autism-and-premature-death#article","url":"https://www.mentalhealth.com/library/autism-and-premature-death","headline":"Autism Spectrum Disorder and Premature Death","description":"Explore the health risks associated with autism and how early interventions, comprehensive care, and supportive strategies can improve outcomes.","wordCount":1402,"mainEntityOfPage":{"@id":"https://www.mentalhealth.com/library/autism-and-premature-death#webpage"},"publisher":{"@id":"https://www.mentalhealth.com/#organization"},"articleSection":"Autism Spectrum Disorder","citation":[{"@type":"CreativeWork","name":"Hirvikoski, T., Mittendorfer-Rutz, E., Boman, M., Larsson, H., Lichtenstein, P., & Bölte, S. 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