{"formatVersion":"1.1","id":"https://www.mentalhealth.com/library/benzodiazepines","path":"/library/benzodiazepines","url":"https://www.mentalhealth.com/library/benzodiazepines","title":"Benzodiazepines","family":"Library detail","description":"Discover how benzodiazepines reduce anxiety and panic, and why safe, short-term use is important for managing dependence risk.","language":"en-US","access":{"audience":"custom-shared-preview","indexable":true},"provenance":{"sourceUrl":"https://www.mentalhealth.com/library/benzodiazepines","wordpressId":"597","contentCompleteness":"complete","dateScope":"original-source"},"authors":[{"@type":"Person","@id":"https://www.mentalhealth.com/people/linda-armstrong#person","name":"Linda Armstrong","url":"https://www.mentalhealth.com/people/linda-armstrong"}],"reviewer":{"@type":"Person","@id":"https://www.mentalhealth.com/people/holly-schiff#person","name":"Holly Schiff, Psy.D.","url":"https://www.mentalhealth.com/people/holly-schiff"},"dates":{"datePublished":"2025-08-08T10:23:37Z","dateModified":"2026-05-28T03:49:21Z","lastReviewed":"2025-08-08"},"content":{"html":"<nav class=\"breadcrumbs\" aria-label=\"Breadcrumb\"><ol><li><a href=\"https://www.mentalhealth.com/\">Home</a></li><li><a href=\"https://www.mentalhealth.com/library\">Library</a></li><li><a href=\"https://www.mentalhealth.com/library/medications\">Medications</a></li><li><span aria-current=\"page\">Benzodiazepines</span></li></ol></nav><div class=\"article-page article-standard\" data-library-standard><div class=\"article-main-grid\"><header class=\"article-heading\"><h1>Benzodiazepines</h1><p class=\"article-inline-credits\"><span>Written by <a class=\"article-credit-person\" href=\"https://www.mentalhealth.com/people/linda-armstrong\"><img src=\"https://www.mentalhealth.com/assets/wordpress/11501.jpg\" alt=\"\" width=\"22\" height=\"22\" loading=\"lazy\">Linda Armstrong</a></span><span>Medically reviewed by <a class=\"article-credit-person\" href=\"https://www.mentalhealth.com/people/holly-schiff\"><img src=\"https://www.mentalhealth.com/assets/wordpress/11503.jpg\" alt=\"\" width=\"22\" height=\"22\" loading=\"lazy\">Holly Schiff, Psy.D.</a></span></p><div class=\"article-dates\"><span>Published on <time datetime=\"2025-08-08T10:23:37Z\">August 8, 2025</time></span><span aria-hidden=\"true\"> · </span><span>Updated on <time datetime=\"2026-05-28T03:49:21Z\">May 28, 2026</time></span></div></header><div class=\"article-jumpbar\"></div><div class=\"article-layout\"><div class=\"article-reading\"><article class=\"prose\" id=\"article-content\"><div class=\"article-intro\" data-source-field=\"hero\"><p>For someone dealing with conditions such as anxiety, insomnia, and prolonged seizures, benzodiazepines can offer fast-acting relief. However, these central nervous system depressants also carry risks, as use can lead to <a href=\"https://www.mentalhealth.com/library/addiction\" class=\"article-inline-link\">dependence and addiction</a>, making medical oversight essential.</p><p>Having clear information about how benzodiazepines are used, their side effects, and their potential for addiction can help people make informed, safer decisions.</p></div><figure class=\"article-feature\"><img src=\"https://www.mentalhealth.com/assets/library/editorial-13512.webp\" alt=\"A counselor takes notes during a conversation with an adult.\" width=\"1200\" height=\"600\" loading=\"eager\" decoding=\"async\"></figure><section class=\"article-takeaways\" aria-labelledby=\"key-takeaways\"><h2 id=\"key-takeaways\">Key takeaways</h2><ul><li>Benzodiazepines enhance the calming effects of GABA, offering fast relief for anxiety, insomnia, and seizures.</li><li>Benzodiazepines are typically prescribed for short-term use, since longer use can lead to dependence, withdrawal, and addiction.</li><li>Combining benzodiazepines with alcohol or opioids is especially dangerous and can cause life-threatening respiratory depression.</li></ul></section><h2 id=\"what-are-benzodiazepines\">What Are Benzodiazepines?</h2><p>Benzodiazepine medications (aka benzos) are <a href=\"https://www.mentalhealth.com/library/medications\" class=\"article-inline-link\">sedative-hypnotic drugs</a> that enhance the effect of gamma-aminobutyric acid (GABA), a type of neurotransmitter that slows nerve activity in the brain and body. This produces a short-term calming effect that helps ease anxiety, muscle tension, and <a href=\"https://www.mentalhealth.com/library/sleep-disorders\" class=\"article-inline-link\">sleep disruption</a> <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>.</p><p>Given their potential benefits, a host of benzodiazepines are prescribed for therapeutic use. In fact, according to the <a href=\"https://www.samhsa.gov/data/report/2023-nsduh-detailed-tables?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-benzodiazepines&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"article-inline-link\">2023 National Survey on Drug Use and Health (NSDUH)</a>, an estimated 23.89 million people aged 12 or older used prescription benzodiazepines in the past year <a href=\"#national-survey-drug-use-health-2023\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\"><sup>[2]</sup></a>. </p><p>That said, the relaxing and potentially euphoric effects of benzodiazepines also mean they can be habit-forming. Among those who use prescription benzodiazepines, 3.69 million reported misusing them <a href=\"#national-survey-drug-use-health-2023\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\"><sup>[2]</sup></a>.</p><p>Perhaps not surprisingly, the U.S. Drug Enforcement Administration classifies most benzodiazepines as Schedule IV controlled substances. This means they have accepted medical uses but also carry the potential for misuse and dependence, and possession without a prescription is illegal <a href=\"#benzodiazepines\" aria-label=\"Reference 3\" class=\"article-inline-link article-citation\"><sup>[3]</sup></a>. </p><p>Significantly, <a href=\"https://www.mentalhealth.com/library/prescription-drug-abuse\" class=\"article-inline-link\">benzodiazepine misuse </a>is also associated with potentially fatal overdose and dangerous interactions with alcohol and other sedative drugs. Plus, benzodiazepines have the potential to be used to perpetrate sexual assault.</p><p>Specifically, rohypnol pills (aka roofies) are linked to sexual assaults during which the victim is rendered unable to understand, resist, or remember the experience <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>. Thus, while these medications can offer significant symptom relief when used appropriately, they also require care and oversight. </p><h2 id=\"common-benzodiazepine-uses\">Common Benzodiazepine Uses</h2><p>Typically administered via oral and intravenous routes, benzodiazepines are most commonly prescribed to treat conditions that involve heightened nervous system activity. Thanks to their fast-acting effects, they can bring noticeable relief within minutes to hours <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>. </p><p>Common conditions treated with benzodiazepines include <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a> <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>: </p><ul class=\"wp-block-list\">\n<li><a href=\"https://www.mentalhealth.com/library/alcohol-use-disorder\" class=\"article-inline-link\">Alcohol withdrawal syndrome</a></li>\n<li><a href=\"https://www.mentalhealth.com/library/anxiety\" class=\"article-inline-link\">Anxiety and panic disorders </a></li>\n<li><a href=\"https://www.mentalhealth.com/library/insomnia-when-sleeping-pills-dont-work\" class=\"article-inline-link\">Insomnia</a></li>\n<li>Prolonged or repetitive seizures</li>\n<li>Spastic and seizure disorders</li>\n<li>Surgery-related sedation</li>\n</ul><p>Various prescription substances are regularly used for off-label purposes, which means the medication is prescribed for a condition that the Food and Drug Administration hasn’t approved. Off-label uses for benzodiazepines include delirium, delirium tremens, <a href=\"https://www.mentalhealth.com/library/sleep-disorders\" class=\"article-inline-link\">sleep disorders</a>, <a href=\"https://www.mentalhealth.com/library/neurological-genetic-disorders\" class=\"article-inline-link\">Tourette syndrome</a>, tremors, tics, and tardive dyskinesia <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>.</p><p>While benzodiazepines offer significant therapeutic benefits, they’re generally intended for short-term use. With prolonged use, the brain may begin to rely on the drug to regulate its activity, which can lead to dependence, withdrawal, and addiction. Because of these risks, medical supervision is essential <a href=\"#benzodiazepines-uses-dangers-clinical-considerations\" aria-label=\"Reference 5\" class=\"article-inline-link article-citation\"><sup>[5]</sup></a>. </p><h2 id=\"types-of-benzodiazepines\">Types of Benzodiazepines</h2><p>Benzodiazepines fall into two main categories based on how long their effects last in the body, namely short-acting and long-acting formulations. The duration of action influences how these medications work for different conditions <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>. </p><p>Short-acting benzodiazepines take effect quickly and remain active in the body for shorter periods. These medications help with conditions requiring immediate relief, such as panic attacks and acute insomnia.</p><p>Meanwhile, long-acting benzodiazepines stay in the body longer, providing extended symptom relief. These medications help people manage chronic conditions like <a href=\"https://www.mentalhealth.com/library/generalized-anxiety-disorder\" class=\"article-inline-link\">generalized anxiety disorder</a> <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>. </p><p>Some of the most commonly prescribed benzodiazepines and their FDA-approved therapeutic uses include <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>: </p><ul class=\"wp-block-list\">\n<li><a href=\"https://www.mentalhealth.com/library/alprazolam-xanax-uses-dosage-side-effects\" class=\"article-inline-link\">Alprazolam (Xanax)</a><strong>: </strong>Anxiety, panic, and premenstrual dysphoric disorder</li>\n<li><a href=\"https://www.mentalhealth.com/library/clonazepam-uses-dosage-side-effects\" class=\"article-inline-link\">Clonazepam (Klonopin)</a><strong>: </strong>Agitation, anxiety, and seizures</li>\n<li><strong><a href=\"https://www.mentalhealth.com/library/diazepam-uses-dosage-side-effects\" class=\"article-inline-link\">Diazepam (Diastat, Valium, Valtoco)</a>:</strong> Muscle spasms, alcohol withdrawal syndrome, seizures, surgical pre-anesthesia</li>\n<li><strong><a href=\"https://www.mentalhealth.com/library/lorazepam-uses-dosage-side-effects\" class=\"article-inline-link\">Lorazepam (Ativan, Loreev)</a>:</strong> Seizures, anxiety, phobias, chemotherapy-related nausea and vomiting, surgical pre-anesthesia</li>\n<li><strong>Quazepam (Doral):</strong> Insomnia and sleep disturbances</li>\n<li><strong><a href=\"https://www.mentalhealth.com/library/temazepam-uses-dosage-side-effects\" class=\"article-inline-link\">Temazepam (Restoril)</a>: </strong>Insomnia</li>\n<li><strong><a href=\"https://www.mentalhealth.com/library/triazolam-halcion-uses-dosage-side-effects\" class=\"article-inline-link\">Triazolam (Halcion)</a>:</strong> Insomnia</li>\n</ul><p>Each benzodiazepine has its risks and duration of onset and effectiveness, making professional oversight essential when choosing the appropriate medication. The right option depends on both the condition being treated and the person’s specific needs and history.</p><h2 id=\"benzodiazepine-side-effects-and-risks\">Benzodiazepine Side Effects and Risks</h2><p>Each type of benzodiazepine is slightly different, and as such, side effects vary by substance. However, as a drug class, benzodiazepines are associated with the following common adverse effects, which can range from mild to severe <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>: </p><ul class=\"wp-block-list\">\n<li>Confusion</li>\n<li>Drowsiness</li>\n<li>Fainting </li>\n<li>Headache</li>\n<li>Nausea, vomiting, and diarrhea</li>\n<li>Respiratory depression and arrest</li>\n<li>Tremors</li>\n</ul><p>Long-term benzodiazepine use can lead to more significant health concerns such as <a href=\"https://www.mentalhealth.com/library/measurement-of-cognitive-capabilities\" class=\"article-inline-link\">cognitive impairment</a>, liver injury, and hypertension. Additionally, specific populations face heightened risks.</p><p>For example, among older adults, benzodiazepines offer an increased risk of cognitive impairment, falls, and accidents. Meanwhile, use of some <a href=\"https://www.mentalhealth.com/library/pregnancy\" class=\"article-inline-link\">benzodiazepines during pregnancy</a> is associated with various forms of fetal risk, and use while breastfeeding should generally be avoided <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>.</p><p>Benzodiazepines can also produce dangerous effects when mixed with alcohol, other benzodiazepines, and various substances that cause sedation (e.g., <a href=\"https://www.mentalhealth.com/library/barbiturates\" class=\"article-inline-link\">barbiturates</a>, <a href=\"https://www.mentalhealth.com/library/opioids\" class=\"article-inline-link\">opioids</a>, and <a href=\"https://www.mentalhealth.com/library/alcohol-use-disorder\" class=\"article-inline-link\">alcohol</a>) <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>.  </p><p>Polysubstance use, which is when two or more substances are intentionally or unintentionally taken together, is never safe, as the combined effect can be stronger and more unpredictable than expected <a href=\"#polysubstance-use-facts\" aria-label=\"Reference 6\" class=\"article-inline-link article-citation\"><sup>[6]</sup></a>. However, when benzodiazepines are combined with other <a href=\"https://www.mentalhealth.com/library/sedative-hypnotic-or-anxiolytic-use-disorder\" class=\"article-inline-link\">sedating substances</a> such as <a href=\"https://www.mentalhealth.com/library/opioids\" class=\"article-inline-link\">opioids</a>, it can lead to severe respiratory depression and death <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>.</p><p>For these and other reasons, healthcare providers closely monitor side effects and use. Any new or worsening symptoms should prompt immediate discussion with a medical professional to ensure safe and effective treatment.</p><h2 id=\"misuse-and-addiction-concerns\">Misuse and Addiction Concerns</h2><p>While benzodiazepines can offer short-term relief from distressing symptoms, they’re also commonly misused. Misuse may involve taking higher doses than prescribed, using someone else’s medication, or mixing benzodiazepines with other substances to intensify their effects <a href=\"#benzodiazepines-source\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\"><sup>[4]</sup></a>.</p><p>When misuse escalates, the body may no longer respond to the drug in the same way, requiring higher doses to achieve the same effect. This cycle often leads to <a href=\"https://www.benzoinfo.com/addiction-vs-physical-dependence/?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-benzodiazepines&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"article-inline-link\">physical dependence</a>, where stopping or reducing use triggers withdrawal symptoms.</p><p>In some cases, misuse progresses into a condition known as <a href=\"https://www.mentalhealth.com/library/sedative-hypnotic-or-anxiolytic-use-disorder\" class=\"article-inline-link\">sedative, hypnotic, or anxiolytic use disorder</a>, a diagnosable <a href=\"https://www.mentalhealth.com/library/substance-use-disorders\" class=\"article-inline-link\">substance use disorder</a> recognized in the Diagnostic and Statistical Manual of Mental Disorders <a href=\"#diagnostic-statistical-manual-mental-disorders-5th-ed\" aria-label=\"Reference 7\" class=\"article-inline-link article-citation\"><sup>[7]</sup></a>.</p><h3 id=\"benzodiazepine-withdrawal\">Benzodiazepine Withdrawal</h3><p>When someone has developed dependence and abruptly stops taking benzodiazepines or significantly limits their use, their body may experience withdrawal as it adjusts to functioning without the drug.</p><p>Physical symptoms of benzodiazepine withdrawal can include headaches, seizures, weakness, fatigue, tremors, gastrointestinal symptoms, and more.</p><p>Additionally, psychological symptoms can include anxiety, insomnia, depression, hallucinations, delirium, and psychosis <a href=\"#benzodiazepines-uses-dangers-clinical-considerations\" aria-label=\"Reference 5\" class=\"article-inline-link article-citation\"><sup>[5]</sup></a>. Due to these risks, medical supervision during withdrawal and detox is essential. </p><p>Healthcare providers typically create <a href=\"https://www.mentalhealth.com/library/other-stimulants\" class=\"article-inline-link\">personalized tapering schedules</a>, gradually reducing the medication dose over time to minimize withdrawal symptoms and ensure safety. This careful approach helps prevent severe complications while supporting the person through the withdrawal process.</p><h3 id=\"illicit-distribution-and-overdose\">Illicit Distribution and Overdose</h3><p>Illicit distribution of benzodiazepines adds another layer of concern. Although these medications are often legally prescribed, they are also widely diverted for nonmedical use and frequently sold illegally. Illicit substances are often obtained through forged prescriptions, online purchases, or theft from pharmacies or patients <a href=\"#benzodiazepines\" aria-label=\"Reference 3\" class=\"article-inline-link article-citation\"><sup>[3]</sup></a>.</p><p>What’s more, illicit drugs often comprise counterfeit pills made with a mixture of potentially dangerous substances (e.g., fentanyl and xylazine). These fake medications pose severe risks, as people may unknowingly consume potentially lethal combinations or doses of substances. </p><p>If someone is suspected of experiencing an overdose, the Centers for Disease Control and Prevention recommends the following steps <a href=\"#do-if-you-think-someone-overdosing\" aria-label=\"Reference 8\" class=\"article-inline-link article-citation\"><sup>[8]</sup></a>:</p><ul class=\"wp-block-list\">\n<li>Call 911 and administer an overdose reversal medication like naloxone (if available).</li>\n<li>Keep the person awake and breathing.</li>\n<li>Lay the person on their side to prevent choking.</li>\n<li>Stay with the person until emergency assistance arrives.</li>\n</ul><h3 id=\"benzodiazepine-addiction-treatment\">Benzodiazepine Addiction Treatment</h3><p>While benzodiazepine addiction can be challenging, recovery is possible with proper care and support. The journey begins with a thorough medical evaluation to determine the most appropriate treatment approach. Following <a href=\"https://www.mentalhealth.com/library/assessments-diagnosis\" class=\"article-inline-link\">clinical evaluation</a>, treatment options range from intensive inpatient care to flexible outpatient programs. </p><p>As the most intensive level of care, <a href=\"https://www.mentalhealth.com/rehab\" class=\"article-inline-link\">residential programs</a> offer comprehensive support in a controlled environment. For those who can maintain daily responsibilities, partial hospitalization programs (PHPs), intensive outpatient programs (IOPs), and standard outpatient programs provide structured support with varying levels of flexibility. </p><p>Regardless of the level of care, successful <a href=\"https://www.mentalhealth.com/library/recovery-from-addiction-social-support\" class=\"article-inline-link\">addiction recovery</a> is built on individualized treatment, medical supervision, and ongoing support tailored to each person’s unique needs.</p><h2 id=\"safe-benzodiazepine-use\">Safe Benzodiazepine Use</h2><p>Safe use of benzodiazepines starts with following prescribed dosages and treatment durations. Healthcare providers typically recommend these medications for short-term use to reduce the risk of dependence. </p><p>However, people taking benzodiazepines must also stay alert to signs of developing dependence, such as needing higher doses to achieve the same effects, experiencing increased symptoms between doses, or thinking about the medication frequently. Meanwhile, regular check-ins with medical providers help monitor effectiveness and address any concerns that arise during treatment <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>.</p><p>For some conditions, alternative treatment options can complement or replace benzodiazepine use. Other medication classes, such as certain <a href=\"https://www.mentalhealth.com/library/antidepressants\" class=\"article-inline-link\">antidepressants</a>, can help manage anxiety with less risk of dependence.</p><p>Nonmedication approaches, including <a href=\"https://www.mentalhealth.com/library/cognitive-behavioral-therapy\" class=\"article-inline-link\">cognitive behavioral therapy</a>, <a href=\"https://www.mentalhealth.com/blog/its-official-relaxation-is-necessary-for-health\" class=\"article-inline-link\">relaxation techniques</a>, and <a href=\"https://www.mentalhealth.com/library/lifestyle-and-depression\" class=\"article-inline-link\">lifestyle modifications</a>, provide additional tools for managing symptoms. These alternatives often offer long-term benefits without some of the risks associated with benzodiazepine use <a href=\"#benzodiazepines-benzos\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\"><sup>[1]</sup></a>.</p><h2 id=\"finding-balance-with-benzodiazepines\">Finding Balance With Benzodiazepines</h2><p>When used as prescribed, benzodiazepines can treat various conditions and improve quality of life. Treating everything from anxiety and insomnia to seizures and alcohol withdrawal, they serve as valuable tools in short-term care. However, with these benefits come risks, especially when use extends beyond <a href=\"https://www.mentalhealth.com/library/psychiatry\" class=\"article-inline-link\">medical guidance</a> or these <a href=\"https://www.mentalhealth.com/library/substance-use-disorders\" class=\"article-inline-link\">substances are misused</a>.</p><p>The path to <a href=\"https://www.mentalhealth.com/library/health-wellness\" class=\"article-inline-link\">optimal health</a> often involves balancing the benefits of these medications with proper precautions. By working closely with healthcare providers, following prescribed guidelines, and staying informed about potential risks, people can maximize the therapeutic benefits while maintaining their safety. </p><p>With the proper care and information, people can make empowered choices, balancing symptom relief with long-term well-being.</p></article><div class=\"article-endmatter\"><section class=\"article-sources\" id=\"references\" data-source-references=\"\" data-reference-list=\"\" data-reference-style=\"author-date-numbered\"><h2 id=\"references-2\">References</h2><ol>\n    <li id=\"benzodiazepines-benzos\" aria-level=\"1\" data-reference-number=\"1\"><span>Cleveland  Clinic. (2023, January 3). </span><i><span>Benzodiazepines (Benzos).</span></i><span> Cleveland Clinic. </span> <a href=\"https://my.clevelandclinic.org/health/treatments/24570-benzodiazepines-benzos\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Cleveland Clinic</a><span>.</span></li>\n    <li id=\"national-survey-drug-use-health-2023\" aria-level=\"1\" data-reference-number=\"2\"><span>U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. (2024). </span><i><span>National Survey on Drug Use and Health 2023</span></i><span>. Table 1.18A. (NSDUH-2016-DS0001). </span> <a href=\"https://www.samhsa.gov/data/report/2023-nsduh-detailed-tables\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Substance Abuse and Mental Health Services Administration (SAMHSA)</a><span>. </span></li>\n    <li id=\"benzodiazepines\" aria-level=\"1\" data-reference-number=\"3\"><span>U.S. Drug Enforcement Administration. (2025). </span><i><span>Benzodiazepines. </span></i><span>U.S. Drug Enforcement Administration. </span> <a href=\"https://www.deadiversion.usdoj.gov/drug_chem_info/benzo.pdf\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Benzodiazepines</a><span>. </span></li>\n    <li id=\"benzodiazepines-source\" aria-level=\"1\" data-reference-number=\"4\"><span>Bounds, C.G., &amp; Patel, P. (2024, January 30). </span><i><span>Benzodiazepines.</span></i><span> In StatPearls</span><i><span>. </span></i><span>StatPearls Publishing. </span> <a href=\"https://www.ncbi.nlm.nih.gov/books/NBK470159/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">National Library of Medicine</a><span>.</span></li>\n    <li id=\"benzodiazepines-uses-dangers-clinical-considerations\" aria-level=\"1\" data-reference-number=\"5\"><span>Edinoff, A. N., Nix, C. A., Hollier, J., Sagrera, C. E., Delacroix, B. M., Abubakar, T., Cornett, E. M., Kaye, A. M., &amp; Kaye, A. D. (2021). Benzodiazepines: Uses, dangers, and clinical considerations. </span><i><span>Neurology International,</span></i> <i><span>13</span></i><span>(4), 594–607. </span> <a href=\"https://doi.org/10.3390/neurolint13040059\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Benzodiazepines</a><span>.</span></li>\n    <li id=\"polysubstance-use-facts\" aria-level=\"1\" data-reference-number=\"6\"><span>Centers for Disease Control and Prevention. (2024, April 2). </span><i><span>Polysubstance use facts.</span></i><span> Centers for Disease Control and Prevention. </span> <a href=\"https://www.cdc.gov/stop-overdose/caring/polysubstance-use.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">CDC</a><span>. </span></li>\n    <li id=\"diagnostic-statistical-manual-mental-disorders-5th-ed\" aria-level=\"1\" data-reference-number=\"7\"><span>American Psychiatric Association. (2022). </span><i><span>Diagnostic and statistical manual of mental disorders</span></i><span> (5th ed. text rev.). </span> <a href=\"https://www.psychiatry.org/psychiatrists/practice/dsm\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">American Psychiatric Association</a><span>.</span></li>\n    <li id=\"do-if-you-think-someone-overdosing\" aria-level=\"1\" data-reference-number=\"8\">Centers for Disease Control and Prevention. (2024, April 2). <i>What to do if you think someone is overdosing. </i>Centers for Disease Control and Prevention. <a href=\"https://www.cdc.gov/stop-overdose/response/index.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">CDC</a>.</li>\n</ol></section><section class=\"article-medical article-panel\"><h2 id=\"medical-content\">Medical Content</h2><p><a href=\"https://www.mentalhealth.com/clinical-affairs\">The Clinical Affairs Team</a> at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the <a href=\"https://www.mentalhealth.com/publishing/editorial-policy\">Editorial Policy</a>.</p></section><section class=\"article-about article-panel\"><h2 id=\"about-mentalhealth-com\">About MentalHealth.com</h2><p>MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.</p><div class=\"article-contributors\"><section class=\"article-bio\"><img src=\"https://www.mentalhealth.com/assets/wordpress/11501.jpg\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><div><p class=\"article-bio-role\">Author</p><h3 id=\"linda-armstrong\"><a href=\"https://www.mentalhealth.com/people/linda-armstrong\">Linda Armstrong</a></h3><p class=\"article-bio-credentials\">Writer</p><p>Linda Armstrong is an award-winning writer and editor with over 20 years of experience across print and digital media.</p><dl><div><dt>Published</dt><dd><time datetime=\"2025-08-08T10:23:37Z\">August 8, 2025</time></dd></div><div><dt>Updated</dt><dd><time datetime=\"2026-05-28T03:49:21Z\">May 28, 2026</time></dd></div></dl></div></section><section class=\"article-bio\"><img src=\"https://www.mentalhealth.com/assets/wordpress/11503.jpg\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><div><p class=\"article-bio-role\">Medical Reviewer</p><h3 id=\"holly-schiff-psy-d\"><a href=\"https://www.mentalhealth.com/people/holly-schiff\">Holly Schiff, Psy.D.</a></h3><p class=\"article-bio-credentials\">Psy.D.</p><p>Holly Schiff, Psy.D., is a licensed clinical psychologist specializing in the treatment of children, young adults, and their families.</p><dl><div><dt>Reviewed</dt><dd><time datetime=\"2025-08-08\">August 8, 2025</time></dd></div></dl></div></section></div></section><section class=\"article-expert article-expert-mobile\" aria-label=\"Subject matter expert\" data-expert-kind=\"related\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><img src=\"https://www.mentalhealth.com/assets/wordpress/3060.webp\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><h2><a href=\"https://www.mentalhealth.com/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h2></div><p class=\"article-expert-focus\">Clinical pharmacy and medication</p><a class=\"profile-experience-link experience-button\" href=\"https://www.mentalhealth.com/people/leila-khurshid\">View experience</a></section><section class=\"article-topic-community article-topic-community-mobile\" aria-label=\"Related communities\"><img class=\"topic-community-banner\" src=\"https://www.mentalhealth.com/assets/library/editorial-17234.webp\" alt=\"\" width=\"48\" height=\"48\" loading=\"lazy\"><p class=\"topic-community-label\">Related communities</p><h2>Medications</h2><p>Explore questions and perspectives about psychiatric medications and the treatment experience.</p><a href=\"https://www.mentalhealth.com/community/medications\">Explore community</a></section></div></div><aside class=\"article-sidebar\" tabindex=\"0\" data-bounded-rail=\"\" aria-label=\"Article navigation and related information\"><details class=\"article-contents\" open data-section-preview=\"3\" data-expanded=\"false\" data-scrolled-past=\"false\"><summary><strong>Table of contents</strong><span aria-hidden=\"true\"></span><small data-current-section=\"\">Choose a section</small></summary><nav aria-label=\"Article contents\"><ol id=\"article-section-list\"><li><a href=\"#what-are-benzodiazepines\" title=\"What Are Benzodiazepines?\" aria-label=\"What Are Benzodiazepines?\">What Are Benzodiazepines?</a></li><li><a href=\"#common-benzodiazepine-uses\" title=\"Common Benzodiazepine Uses\" aria-label=\"Common Benzodiazepine Uses\">Common Benzodiazepine Uses</a></li><li><a href=\"#types-of-benzodiazepines\" title=\"Types of Benzodiazepines\" aria-label=\"Types of Benzodiazepines\">Types of Benzodiazepines</a></li><li><a href=\"#benzodiazepine-side-effects-and-risks\" title=\"Benzodiazepine Side Effects and Risks\" aria-label=\"Benzodiazepine Side Effects and Risks\">Benzodiazepine Side Effects and Risks</a></li><li><a href=\"#misuse-and-addiction-concerns\" title=\"Misuse and Addiction Concerns\" aria-label=\"Misuse and Addiction Concerns\">Misuse and Addiction Concerns</a></li><li><a href=\"#safe-benzodiazepine-use\" title=\"Safe Benzodiazepine Use\" aria-label=\"Safe Benzodiazepine Use\">Safe Benzodiazepine Use</a></li><li><a href=\"#finding-balance-with-benzodiazepines\" title=\"Finding Balance With Benzodiazepines\" aria-label=\"Finding Balance With Benzodiazepines\">Finding Balance With Benzodiazepines</a></li></ol><button type=\"button\" class=\"article-sections-toggle\" data-sections-toggle aria-controls=\"article-section-list\" aria-expanded=\"false\">View more</button></nav></details><section class=\"article-expert\" aria-label=\"Subject matter expert\" data-expert-kind=\"related\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><img src=\"https://www.mentalhealth.com/assets/wordpress/3060.webp\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><h2><a href=\"https://www.mentalhealth.com/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h2></div><p class=\"article-expert-focus\">Clinical pharmacy and medication</p><a class=\"profile-experience-link experience-button\" href=\"https://www.mentalhealth.com/people/leila-khurshid\">View experience</a></section><section class=\"article-topic-community\" aria-label=\"Related communities\"><img class=\"topic-community-banner\" src=\"https://www.mentalhealth.com/assets/library/editorial-17234.webp\" alt=\"\" width=\"48\" height=\"48\" loading=\"lazy\"><p class=\"topic-community-label\">Related communities</p><h2>Medications</h2><p>Explore questions and perspectives about psychiatric medications and the treatment experience.</p><a href=\"https://www.mentalhealth.com/community/medications\">Explore community</a></section></aside></div></div></div>","text":"HomeLibraryMedicationsBenzodiazepinesBenzodiazepinesWritten by Linda ArmstrongMedically reviewed by Holly Schiff, Psy.D.Published on August 8, 2025 · Updated on May 28, 2026For someone dealing with conditions such as anxiety, insomnia, and prolonged seizures, benzodiazepines can offer fast-acting relief. However, these central nervous system depressants also carry risks, as use can lead to dependence and addiction, making medical oversight essential.Having clear information about how benzodiazepines are used, their side effects, and their potential for addiction can help people make informed, safer decisions.Key takeawaysBenzodiazepines enhance the calming effects of GABA, offering fast relief for anxiety, insomnia, and seizures.Benzodiazepines are typically prescribed for short-term use, since longer use can lead to dependence, withdrawal, and addiction.Combining benzodiazepines with alcohol or opioids is especially dangerous and can cause life-threatening respiratory depression.What Are Benzodiazepines?Benzodiazepine medications (aka benzos) are sedative-hypnotic drugs that enhance the effect of gamma-aminobutyric acid (GABA), a type of neurotransmitter that slows nerve activity in the brain and body. This produces a short-term calming effect that helps ease anxiety, muscle tension, and sleep disruption [1].Given their potential benefits, a host of benzodiazepines are prescribed for therapeutic use. In fact, according to the 2023 National Survey on Drug Use and Health (NSDUH), an estimated 23.89 million people aged 12 or older used prescription benzodiazepines in the past year [2]. That said, the relaxing and potentially euphoric effects of benzodiazepines also mean they can be habit-forming. Among those who use prescription benzodiazepines, 3.69 million reported misusing them [2].Perhaps not surprisingly, the U.S. Drug Enforcement Administration classifies most benzodiazepines as Schedule IV controlled substances. This means they have accepted medical uses but also carry the potential for misuse and dependence, and possession without a prescription is illegal [3]. Significantly, benzodiazepine misuse is also associated with potentially fatal overdose and dangerous interactions with alcohol and other sedative drugs. Plus, benzodiazepines have the potential to be used to perpetrate sexual assault.Specifically, rohypnol pills (aka roofies) are linked to sexual assaults during which the victim is rendered unable to understand, resist, or remember the experience [1]. Thus, while these medications can offer significant symptom relief when used appropriately, they also require care and oversight. Common Benzodiazepine UsesTypically administered via oral and intravenous routes, benzodiazepines are most commonly prescribed to treat conditions that involve heightened nervous system activity. Thanks to their fast-acting effects, they can bring noticeable relief within minutes to hours [1]. Common conditions treated with benzodiazepines include [1] [4]: Alcohol withdrawal syndrome Anxiety and panic disorders Insomnia Prolonged or repetitive seizures Spastic and seizure disorders Surgery-related sedation Various prescription substances are regularly used for off-label purposes, which means the medication is prescribed for a condition that the Food and Drug Administration hasn’t approved. Off-label uses for benzodiazepines include delirium, delirium tremens, sleep disorders, Tourette syndrome, tremors, tics, and tardive dyskinesia [4].While benzodiazepines offer significant therapeutic benefits, they’re generally intended for short-term use. With prolonged use, the brain may begin to rely on the drug to regulate its activity, which can lead to dependence, withdrawal, and addiction. Because of these risks, medical supervision is essential [5]. Types of BenzodiazepinesBenzodiazepines fall into two main categories based on how long their effects last in the body, namely short-acting and long-acting formulations. The duration of action influences how these medications work for different conditions [1]. Short-acting benzodiazepines take effect quickly and remain active in the body for shorter periods. These medications help with conditions requiring immediate relief, such as panic attacks and acute insomnia.Meanwhile, long-acting benzodiazepines stay in the body longer, providing extended symptom relief. These medications help people manage chronic conditions like generalized anxiety disorder [1]. Some of the most commonly prescribed benzodiazepines and their FDA-approved therapeutic uses include [1]: Alprazolam (Xanax): Anxiety, panic, and premenstrual dysphoric disorder Clonazepam (Klonopin): Agitation, anxiety, and seizures Diazepam (Diastat, Valium, Valtoco): Muscle spasms, alcohol withdrawal syndrome, seizures, surgical pre-anesthesia Lorazepam (Ativan, Loreev): Seizures, anxiety, phobias, chemotherapy-related nausea and vomiting, surgical pre-anesthesia Quazepam (Doral): Insomnia and sleep disturbances Temazepam (Restoril): Insomnia Triazolam (Halcion): Insomnia Each benzodiazepine has its risks and duration of onset and effectiveness, making professional oversight essential when choosing the appropriate medication. The right option depends on both the condition being treated and the person’s specific needs and history.Benzodiazepine Side Effects and RisksEach type of benzodiazepine is slightly different, and as such, side effects vary by substance. However, as a drug class, benzodiazepines are associated with the following common adverse effects, which can range from mild to severe [4]: Confusion Drowsiness Fainting Headache Nausea, vomiting, and diarrhea Respiratory depression and arrest Tremors Long-term benzodiazepine use can lead to more significant health concerns such as cognitive impairment, liver injury, and hypertension. Additionally, specific populations face heightened risks.For example, among older adults, benzodiazepines offer an increased risk of cognitive impairment, falls, and accidents. Meanwhile, use of some benzodiazepines during pregnancy is associated with various forms of fetal risk, and use while breastfeeding should generally be avoided [4].Benzodiazepines can also produce dangerous effects when mixed with alcohol, other benzodiazepines, and various substances that cause sedation (e.g., barbiturates, opioids, and alcohol) [4]. Polysubstance use, which is when two or more substances are intentionally or unintentionally taken together, is never safe, as the combined effect can be stronger and more unpredictable than expected [6]. However, when benzodiazepines are combined with other sedating substances such as opioids, it can lead to severe respiratory depression and death [4].For these and other reasons, healthcare providers closely monitor side effects and use. Any new or worsening symptoms should prompt immediate discussion with a medical professional to ensure safe and effective treatment.Misuse and Addiction ConcernsWhile benzodiazepines can offer short-term relief from distressing symptoms, they’re also commonly misused. Misuse may involve taking higher doses than prescribed, using someone else’s medication, or mixing benzodiazepines with other substances to intensify their effects [4].When misuse escalates, the body may no longer respond to the drug in the same way, requiring higher doses to achieve the same effect. This cycle often leads to physical dependence, where stopping or reducing use triggers withdrawal symptoms.In some cases, misuse progresses into a condition known as sedative, hypnotic, or anxiolytic use disorder, a diagnosable substance use disorder recognized in the Diagnostic and Statistical Manual of Mental Disorders [7].Benzodiazepine WithdrawalWhen someone has developed dependence and abruptly stops taking benzodiazepines or significantly limits their use, their body may experience withdrawal as it adjusts to functioning without the drug.Physical symptoms of benzodiazepine withdrawal can include headaches, seizures, weakness, fatigue, tremors, gastrointestinal symptoms, and more.Additionally, psychological symptoms can include anxiety, insomnia, depression, hallucinations, delirium, and psychosis [5]. Due to these risks, medical supervision during withdrawal and detox is essential. Healthcare providers typically create personalized tapering schedules, gradually reducing the medication dose over time to minimize withdrawal symptoms and ensure safety. This careful approach helps prevent severe complications while supporting the person through the withdrawal process.Illicit Distribution and OverdoseIllicit distribution of benzodiazepines adds another layer of concern. Although these medications are often legally prescribed, they are also widely diverted for nonmedical use and frequently sold illegally. Illicit substances are often obtained through forged prescriptions, online purchases, or theft from pharmacies or patients [3].What’s more, illicit drugs often comprise counterfeit pills made with a mixture of potentially dangerous substances (e.g., fentanyl and xylazine). These fake medications pose severe risks, as people may unknowingly consume potentially lethal combinations or doses of substances. If someone is suspected of experiencing an overdose, the Centers for Disease Control and Prevention recommends the following steps [8]: Call 911 and administer an overdose reversal medication like naloxone (if available). Keep the person awake and breathing. Lay the person on their side to prevent choking. Stay with the person until emergency assistance arrives. Benzodiazepine Addiction TreatmentWhile benzodiazepine addiction can be challenging, recovery is possible with proper care and support. The journey begins with a thorough medical evaluation to determine the most appropriate treatment approach. Following clinical evaluation, treatment options range from intensive inpatient care to flexible outpatient programs. As the most intensive level of care, residential programs offer comprehensive support in a controlled environment. For those who can maintain daily responsibilities, partial hospitalization programs (PHPs), intensive outpatient programs (IOPs), and standard outpatient programs provide structured support with varying levels of flexibility. Regardless of the level of care, successful addiction recovery is built on individualized treatment, medical supervision, and ongoing support tailored to each person’s unique needs.Safe Benzodiazepine UseSafe use of benzodiazepines starts with following prescribed dosages and treatment durations. Healthcare providers typically recommend these medications for short-term use to reduce the risk of dependence. However, people taking benzodiazepines must also stay alert to signs of developing dependence, such as needing higher doses to achieve the same effects, experiencing increased symptoms between doses, or thinking about the medication frequently. Meanwhile, regular check-ins with medical providers help monitor effectiveness and address any concerns that arise during treatment [1].For some conditions, alternative treatment options can complement or replace benzodiazepine use. Other medication classes, such as certain antidepressants, can help manage anxiety with less risk of dependence.Nonmedication approaches, including cognitive behavioral therapy, relaxation techniques, and lifestyle modifications, provide additional tools for managing symptoms. These alternatives often offer long-term benefits without some of the risks associated with benzodiazepine use [1].Finding Balance With BenzodiazepinesWhen used as prescribed, benzodiazepines can treat various conditions and improve quality of life. Treating everything from anxiety and insomnia to seizures and alcohol withdrawal, they serve as valuable tools in short-term care. However, with these benefits come risks, especially when use extends beyond medical guidance or these substances are misused.The path to optimal health often involves balancing the benefits of these medications with proper precautions. By working closely with healthcare providers, following prescribed guidelines, and staying informed about potential risks, people can maximize the therapeutic benefits while maintaining their safety. With the proper care and information, people can make empowered choices, balancing symptom relief with long-term well-being.References Cleveland Clinic. (2023, January 3). Benzodiazepines (Benzos). Cleveland Clinic. Cleveland Clinic. U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. (2024). National Survey on Drug Use and Health 2023. Table 1.18A. (NSDUH-2016-DS0001). Substance Abuse and Mental Health Services Administration (SAMHSA). U.S. Drug Enforcement Administration. (2025). Benzodiazepines. U.S. Drug Enforcement Administration. Benzodiazepines. Bounds, C.G., & Patel, P. (2024, January 30). Benzodiazepines. In StatPearls. StatPearls Publishing. National Library of Medicine. Edinoff, A. N., Nix, C. A., Hollier, J., Sagrera, C. E., Delacroix, B. M., Abubakar, T., Cornett, E. M., Kaye, A. M., & Kaye, A. D. (2021). Benzodiazepines: Uses, dangers, and clinical considerations. Neurology International, 13(4), 594–607. Benzodiazepines. Centers for Disease Control and Prevention. (2024, April 2). Polysubstance use facts. Centers for Disease Control and Prevention. CDC. American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed. text rev.). American Psychiatric Association. Centers for Disease Control and Prevention. (2024, April 2). What to do if you think someone is overdosing. Centers for Disease Control and Prevention. CDC. Medical ContentThe Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy.About MentalHealth.comMentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.AuthorLinda ArmstrongWriterLinda Armstrong is an award-winning writer and editor with over 20 years of experience across print and digital media.PublishedAugust 8, 2025UpdatedMay 28, 2026Medical ReviewerHolly Schiff, Psy.D.Psy.D.Holly Schiff, Psy.D., is a licensed clinical psychologist specializing in the treatment of children, young adults, and their families.ReviewedAugust 8, 2025Subject matter expertLeila Khurshid, Pharm.D.Clinical pharmacy and medicationView experienceRelated communitiesMedicationsExplore questions and perspectives about psychiatric medications and the treatment experience.Explore communityTable of contentsChoose a sectionWhat Are Benzodiazepines?Common Benzodiazepine UsesTypes of BenzodiazepinesBenzodiazepine Side Effects and RisksMisuse and Addiction ConcernsSafe Benzodiazepine UseFinding Balance With BenzodiazepinesView moreSubject matter expertLeila Khurshid, Pharm.D.Clinical pharmacy and medicationView experienceRelated communitiesMedicationsExplore questions and perspectives about psychiatric medications and the treatment experience.Explore community","wordCount":2006},"schema":{"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://www.mentalhealth.com/#organization","name":"MentalHealth.com","url":"https://www.mentalhealth.com/"},{"@type":"WebSite","@id":"https://www.mentalhealth.com/#website","url":"https://www.mentalhealth.com/","name":"MentalHealth.com","inLanguage":"en-US","publisher":{"@id":"https://www.mentalhealth.com/#organization"}},{"@type":"BreadcrumbList","@id":"https://www.mentalhealth.com/library/benzodiazepines#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.mentalhealth.com/"},{"@type":"ListItem","position":2,"name":"Library","item":"https://www.mentalhealth.com/library"},{"@type":"ListItem","position":3,"name":"Medications","item":"https://www.mentalhealth.com/library/medications"},{"@type":"ListItem","position":4,"name":"Benzodiazepines","item":"https://www.mentalhealth.com/library/benzodiazepines"}]},{"@type":"ImageObject","@id":"https://www.mentalhealth.com/library/benzodiazepines#primaryimage","url":"https://www.mentalhealth.com/assets/library/editorial-13512.webp","contentUrl":"https://www.mentalhealth.com/assets/library/editorial-13512.webp","width":1200,"height":600,"encodingFormat":"image/webp","caption":"A counselor takes notes during a conversation with an adult."},{"@type":"Person","@id":"https://www.mentalhealth.com/people/linda-armstrong#person","name":"Linda Armstrong","url":"https://www.mentalhealth.com/people/linda-armstrong","jobTitle":"Writer","image":"https://www.mentalhealth.com/assets/wordpress/11501.jpg","sameAs":["https://www.linkedin.com/in/linda-l-armstrong-5a74342/"]},{"@type":"Person","@id":"https://www.mentalhealth.com/people/holly-schiff#person","name":"Holly Schiff, Psy.D.","url":"https://www.mentalhealth.com/people/holly-schiff","jobTitle":"Psy.D.","image":"https://www.mentalhealth.com/assets/wordpress/11503.jpg","sameAs":["https://www.linkedin.com/in/holly-ann-schiff-psy-d-21b53821/"]},{"@type":"Article","@id":"https://www.mentalhealth.com/library/benzodiazepines#article","url":"https://www.mentalhealth.com/library/benzodiazepines","headline":"Benzodiazepines","description":"Discover how benzodiazepines reduce anxiety and panic, and why safe, short-term use is important for managing dependence risk.","wordCount":1646,"mainEntityOfPage":{"@id":"https://www.mentalhealth.com/library/benzodiazepines#webpage"},"publisher":{"@id":"https://www.mentalhealth.com/#organization"},"articleSection":"Library","citation":[{"@type":"CreativeWork","name":"Cleveland Clinic. 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(2023, January 3). Benzodiazepines (Benzos). Cleveland Clinic. Cleveland Clinic.","links":[{"url":"https://my.clevelandclinic.org/health/treatments/24570-benzodiazepines-benzos","label":"Cleveland Clinic"}],"url":"https://my.clevelandclinic.org/health/treatments/24570-benzodiazepines-benzos"},{"number":2,"id":"https://www.mentalhealth.com/library/benzodiazepines#national-survey-drug-use-health-2023","text":"U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. (2024). National Survey on Drug Use and Health 2023. Table 1.18A. (NSDUH-2016-DS0001). Substance Abuse and Mental Health Services Administration (SAMHSA).","links":[{"url":"https://www.samhsa.gov/data/report/2023-nsduh-detailed-tables","label":"Substance Abuse and Mental Health Services Administration (SAMHSA)"}],"url":"https://www.samhsa.gov/data/report/2023-nsduh-detailed-tables"},{"number":3,"id":"https://www.mentalhealth.com/library/benzodiazepines#benzodiazepines","text":"U.S. Drug Enforcement Administration. (2025). Benzodiazepines. U.S. Drug Enforcement Administration. Benzodiazepines.","links":[{"url":"https://www.deadiversion.usdoj.gov/drug_chem_info/benzo.pdf","label":"Benzodiazepines"}],"url":"https://www.deadiversion.usdoj.gov/drug_chem_info/benzo.pdf"},{"number":4,"id":"https://www.mentalhealth.com/library/benzodiazepines#benzodiazepines-source","text":"Bounds, C.G., & Patel, P. (2024, January 30). Benzodiazepines. In StatPearls. StatPearls Publishing. National Library of Medicine.","links":[{"url":"https://www.ncbi.nlm.nih.gov/books/NBK470159/","label":"National Library of Medicine"}],"url":"https://www.ncbi.nlm.nih.gov/books/NBK470159/"},{"number":5,"id":"https://www.mentalhealth.com/library/benzodiazepines#benzodiazepines-uses-dangers-clinical-considerations","text":"Edinoff, A. N., Nix, C. A., Hollier, J., Sagrera, C. E., Delacroix, B. M., Abubakar, T., Cornett, E. M., Kaye, A. M., & Kaye, A. D. (2021). Benzodiazepines: Uses, dangers, and clinical considerations. Neurology International, 13(4), 594–607. Benzodiazepines.","links":[{"url":"https://doi.org/10.3390/neurolint13040059","label":"Benzodiazepines"}],"url":"https://doi.org/10.3390/neurolint13040059"},{"number":6,"id":"https://www.mentalhealth.com/library/benzodiazepines#polysubstance-use-facts","text":"Centers for Disease Control and Prevention. (2024, April 2). Polysubstance use facts. Centers for Disease Control and Prevention. CDC.","links":[{"url":"https://www.cdc.gov/stop-overdose/caring/polysubstance-use.html","label":"CDC"}],"url":"https://www.cdc.gov/stop-overdose/caring/polysubstance-use.html"},{"number":7,"id":"https://www.mentalhealth.com/library/benzodiazepines#diagnostic-statistical-manual-mental-disorders-5th-ed","text":"American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed. text rev.). American Psychiatric Association.","links":[{"url":"https://www.psychiatry.org/psychiatrists/practice/dsm","label":"American Psychiatric Association"}],"url":"https://www.psychiatry.org/psychiatrists/practice/dsm"},{"number":8,"id":"https://www.mentalhealth.com/library/benzodiazepines#do-if-you-think-someone-overdosing","text":"Centers for Disease Control and Prevention. (2024, April 2). What to do if you think someone is overdosing. Centers for Disease Control and Prevention. 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However, these central nervous system depressants also carry risks, as use can lead to <a href=\"https://www.mentalhealth.com/library/addiction\">dependence and addiction</a>, making medical oversight essential.\n\nHaving clear information about how benzodiazepines are used, their side effects, and their potential for addiction can help people make informed, safer decisions.","text":"For someone dealing with conditions such as anxiety, insomnia, and prolonged seizures, benzodiazepines can offer fast-acting relief. However, these central nervous system depressants also carry risks, as use can lead to dependence and addiction, making medical oversight essential. 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