{"formatVersion":"1.1","id":"https://www.mentalhealth.com/library/managing-persistent-depression","path":"/library/managing-persistent-depression","url":"https://www.mentalhealth.com/library/managing-persistent-depression","title":"Managing Persistent Depression","family":"Library detail","description":"Learn about persistent depressive disorder, its symptoms, treatment, and proven tools for recovery, support, and self-care.","language":"en-US","access":{"audience":"public","indexable":true},"provenance":{"sourceUrl":"https://www.mentalhealth.com/library/managing-persistent-depression","wordpressId":"646","contentCompleteness":"complete","dateScope":"original-source"},"authors":[{"@type":"Person","@id":"https://www.mentalhealth.com/people/sue-collier#person","name":"Sue Collier","url":"https://www.mentalhealth.com/people/sue-collier"}],"reviewer":{"@type":"Person","@id":"https://www.mentalhealth.com/people/shivani-kharod#person","name":"Shivani Kharod, Ph.D.","url":"https://www.mentalhealth.com/people/shivani-kharod"},"dates":{"datePublished":"2025-06-05T09:33:37Z","dateModified":"2026-05-12T12:21:51Z","lastReviewed":"2025-06-05"},"content":{"html":"<nav aria-label=\"Breadcrumb\" class=\"breadcrumbs\"><ol><li><a href=\"https://www.mentalhealth.com/\">Home</a></li><li><a href=\"https://www.mentalhealth.com/library\">Library</a></li><li><a href=\"https://www.mentalhealth.com/library/depression\">Depression</a></li><li><span aria-current=\"page\">Managing Persistent Depression</span></li></ol></nav><div class=\"article-page article-standard\" data-library-standard=\"\"><div class=\"article-main-grid\"><header class=\"article-heading\"><h1>Managing Persistent Depression</h1><p class=\"article-inline-credits\"><span class=\"credit-row\"><span>Written by <a class=\"article-credit-person\" href=\"https://www.mentalhealth.com/people/sue-collier\">Sue Collier, B.A.</a></span><span>Medically reviewed by <a class=\"article-credit-person\" href=\"https://www.mentalhealth.com/people/shivani-kharod\">Shivani Kharod, Ph.D.</a></span></span></p><div class=\"article-dates\"><span>Published on <time datetime=\"2025-06-05T09:33:37Z\">June 5, 2025</time></span><span aria-hidden=\"true\"> · </span><span>Updated on <time datetime=\"2026-05-12T12:21:51Z\">May 12, 2026</time></span></div></header><div class=\"article-jumpbar\"></div><div class=\"article-layout\"><div class=\"article-reading\"><article class=\"prose\" id=\"article-content\"><div class=\"article-intro\" data-source-field=\"hero\"><p>People living with <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/dysthymic-disorder\">persistent depressive disorder (PDD)</a> face ongoing depressive symptoms that may seem milder than those of major depression. It can drain energy, dull joy, and make even simple tasks feel overwhelming. It often shows up as chronic sadness, low motivation, and a lack of interest in things that once mattered. Fortunately, several proven strategies can help manage persistent depression and improve daily functioning.</p></div><figure class=\"article-feature\"><img alt=\"A person sits with their hands resting together in their lap.\" decoding=\"async\" height=\"674\" loading=\"eager\" src=\"https://www.mentalhealth.com/assets/optimized/be4f543e0654ec8a3a09f898.webp\" width=\"1200\" srcset=\"/assets/responsive/7ac24e0ce396ff34bfa53399.webp 800w, /assets/optimized/be4f543e0654ec8a3a09f898.webp 1200w\" sizes=\"(max-width: 800px) 100vw, 1200px\"></figure><section aria-labelledby=\"key-takeaways\" class=\"article-takeaways\"><h2 id=\"key-takeaways\">Key takeaways</h2><ul><li>Persistent depressive disorder involves depressive symptoms lasting at least two years in adults or one year in young people.</li><li>Its long duration can drain energy and enjoyment even when a person continues meeting daily responsibilities.</li><li>Consistent treatment, manageable routines, and supportive relationships can promote gradual improvement and sustained recovery.</li></ul></section><h2 id=\"what-makes-persistent-depression-different\">What Makes Persistent Depression Different?</h2><p>Persistent depressive disorder is a <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/depressive-disorders\">chronic form of depression</a> lasting at least two years in adults or one year in children and adolescents⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#depression\" data-reference-link=\"\" aria-label=\"Reference 1: National Institute of Mental Health. (n.d.). Depression. U.S. Department of Health and Human Services. National Institute of Mental Health. Accessed October 10 2026.\" data-reference-number=\"1\">[1]</a></sup>. Also known as dysthymia, its symptoms are less intense than those of major depressive disorder, though they last longer and are more ingrained in daily life.</p><p>People with PDD often describe life as a continuous emotional struggle. They may maintain jobs, care for family, and fulfill responsibilities, yet feel depleted or numb internally. Symptoms develop slowly and linger, often mistaken for personality traits or life circumstances, making early recognition and intervention especially important.</p><section aria-label=\"Subject matter expert\" class=\"article-expert article-expert-inline\" data-expert-kind=\"related\" data-expert-layout=\"standard\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><a href=\"https://www.mentalhealth.com/people/simone-hoermann\" class=\"card-identity-photo\" aria-label=\"Simone Hoermann  Ph.D.\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"https://www.mentalhealth.com/assets/optimized/5ffe249a46895c9a14f6074b.jpg\" width=\"64\" decoding=\"async\"></a><h2><a href=\"https://www.mentalhealth.com/people/simone-hoermann\">Simone Hoermann <span class=\"expert-credentials\">Ph.D.</span></a></h2></div><p class=\"article-expert-focus\">Personality disorders, anxiety, and depression</p><a href=\"https://www.mentalhealth.com/people/simone-hoermann\" class=\"quiet-button\">View profile</a></section><h2 id=\"the-signs-of-persistent-depression\">The Signs of Persistent Depression</h2><p>Symptoms of persistent depressive disorder (PDD), also known as dysthymia, often emerge gradually and can become so ingrained in daily life that they go unnoticed. Over time, these symptoms may become intertwined with a person’s self-perception, making them particularly difficult to recognize and diagnose.</p><p>Still, there are patterns, both behavioral and emotional, that can signal the presence of PDD. These signs may not be dramatic, but they often interfere with relationships, responsibilities, and overall well-being.</p><p>Behavioral changes may include overeating or undereating and sleeping too much or too little. Some people might experience trouble focusing or making decisions, constant fatigue or low energy, delays completing tasks, or reduced work quality. Another sign is withdrawing from social situations or relationships.</p><p>Emotional indicators of persistent depression often reveal themselves in subtle but disruptive ways. Individuals may experience a persistent sense of <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/importance-and-dimensions-of-self-esteem\">low self-worth or ongoing self-doubt</a>, along with feelings of sadness, emptiness, or hopelessness that linger over time. </p><p>Guilt can arise frequently, sometimes triggered by minor concerns, and this emotional weight is often paired with apathy toward activities that once felt meaningful. Heightened sensitivity or irritability may also emerge, making it harder to cope with everyday stressors or social interactions.</p><p>These symptoms can persist for years and often overlap with other conditions. Only about 25%-30% of people with PDD experience it in isolation, without other <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/mental-disorders\">psychiatric disorders</a>⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#epidemiology-dysthymia-five-communities-rates-risks-comorbidity-treatment\" data-reference-link=\"\" aria-label=\"Reference 2: Weissman, M. M., Leaf, P. J., Holzer, C. E., Myers, J. K., &amp; Tischler, G. L. (1988). The epidemiology of dysthymia in five communities: Rates, risks, comorbidity, and treatment. The American Journal of Psychiatry, 145(7), 815–819. PsychiatryOnline. Accessed May 23 2025.\" data-reference-number=\"2\">[2]</a></sup>. </p><h2 id=\"risk-factors-of-persistent-depression\">Risk Factors of Persistent Depression</h2><p>The exact cause of PDD remains unclear, but research suggests multiple contributing factors. According to the Mayo Clinic, persistent depression may stem from a mix of biological, genetic, and psychosocial influences, including⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#persistent-depressive-disorder\" data-reference-link=\"\" aria-label=\"Reference 3: Mayo Clinic. (2023). Persistent depressive disorder. Mayo Clinic. Accessed October 10 2026.\" data-reference-number=\"3\">[3]</a></sup>:</p><ul class=\"wp-block-list\">\n<li><strong>Neurochemical imbalances:</strong> Disruptions in neurotransmitters can impair emotional regulation.</li>\n<li><strong>Genetics:</strong> People with a family history of mood disorders are at higher risk of persistent depression.</li>\n<li><strong>Chronic stress or <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/what-is-trauma\">trauma</a>:</strong> Prolonged life challenges, such as loss or instability, may trigger depressive symptoms.</li>\n<li><strong>Personality traits:</strong> People with low self-esteem or a pessimistic outlook may be more vulnerable to PDD.</li>\n</ul><p>While these factors don’t determine whether someone will develop PDD, they help explain who might be more susceptible and why symptoms often persist over time.</p><h2 id=\"diagnosing-persistent-depression\">Diagnosing Persistent Depression</h2><p>Persistent depression often co-occurs with <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/anxiety\">anxiety</a> or physical illness, and accurate diagnosis requires a comprehensive evaluation. Mental health professionals use psychological assessments, medical and psychiatric histories, and sometimes lab tests to rule out physical causes of symptoms.</p><p>A diagnosis of PDD depends heavily on symptom duration. In general, PPD lasts at least two years in adults and at least one year in children and adolescents⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#persistent-depressive-disorder\" data-reference-link=\"\" aria-label=\"Reference 3: Mayo Clinic. (2023). Persistent depressive disorder. Mayo Clinic. Accessed October 10 2026.\" data-reference-number=\"3\">[3]</a></sup>. Since symptoms mimic other conditions, professionals strongly advise against self-diagnosis. Therefore, it’s important that individuals seek a professional assessment as early diagnosis can significantly improve outcomes.</p><h2 id=\"treatment-approaches-for-managing-pdd\">Treatment Approaches for Managing PDD</h2><p>Once diagnosed, effective management of PDD usually involves a combination of medication, psychotherapy, and lifestyle changes⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#depression-diagnosis-treatment\" data-reference-link=\"\" aria-label=\"Reference 4: Mayo Clinic. (2023). Depression: Diagnosis and treatment. Mayo Clinic. Accessed October 10 2026.\" data-reference-number=\"4\">[4]</a></sup>. Given the chronic nature of the disorder, the treatment approach should be personalized to match each individual's unique needs, </p><p>Medications may include:</p><ul class=\"wp-block-list\">\n<li><strong>SSRIs:</strong> Selective serotonin reuptake inhibitors (SSRIs) such as sertraline or fluoxetine</li>\n<li><strong>SNRIs: </strong>Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine</li>\n<li><strong><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/atypical-antidepressants\">Atypical antidepressants</a>:</strong> Medications such as bupropion</li>\n</ul><p>If initial treatment does not provide complete relief, clinicians may adjust the dosage or introduce additional medications⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#acute-longer-term-outcomes-depressed-outpatients-requiring-one-several\" data-reference-link=\"\" aria-label=\"Reference 5: Rush, A. J., Trivedi, M. H., Wisniewski, S. R., et al. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report. American Journal of Psychiatry, 163(11), 1905–1917. PsychiatryOnline. Accessed May 23 2025.\" data-reference-number=\"5\">[5]</a></sup>. Considering antidepressants typically take several weeks to become effective, regular monitoring is essential to evaluate progress and manage potential side effects.</p><p><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/psychotherapy\">Psychotherapy</a> options include⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#randomized-trial-behavioral-activation-cognitive-therapy-antidepressant-medication-acute\" data-reference-link=\"\" aria-label=\"Reference 6: Dimidjian, S., Hollon, S. D., Dobson, K. S., et al. (2006). Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. Journal of Consulting and Clinical Psychology, 74(4), 658–670. psycnet.apa.org:443. Accessed May 23 2025.\" data-reference-number=\"6\">[6]</a></sup>:</p><ul class=\"wp-block-list\">\n<li><strong><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/cognitive-behavioral-therapy\">Cognitive-Behavioral Therapy (CBT)</a>:</strong> Cognitive behavioral therapy (CBT) targets negative thinking patterns.</li>\n<li><strong>Interpersonal Therapy (IPT):</strong> IPT focuses on relationship dynamics.</li>\n<li><strong><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/psychodynamic-theories\">Psychodynamic therapy</a>:</strong>  Psychodynamic therapy addresses unconscious emotional patterns.</li>\n<li><strong>Behavioral activation:</strong> Behavioral activation includes re-engagement with enjoyable or meaningful activities.</li>\n</ul><p>While medication and therapy are helpful on their own, evidence suggests that combining therapy with medication is especially effective for chronic or treatment-resistant depression.</p><aside class=\"article-support\" data-article-therapist=\"managing-persistent-depression\" aria-label=\"Find support that fits you\"><div><h2>Find support that fits you</h2><p>Explore people and care options near you.</p></div><a href=\"https://www.mentalhealth.com/therapists?specialty=Depression\" target=\"_blank\" rel=\"noopener noreferrer\">Find care</a></aside><h2 id=\"daily-habits-that-support-recovery\">Daily Habits That Support Recovery</h2><p>In addition to clinical treatment, daily habits and lifestyle adjustments play a vital role in managing persistent depression. <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/recovery\">Long-term recovery</a> is often supported not just by what happens in the therapist’s office or with medication but by small, consistent efforts made throughout everyday life.</p><p>Establishing structure and routine can reduce stress and help regulate mood. When low energy or motivation, simple, repeatable actions, such as eating regular meals or maintaining a consistent sleep schedule, can create a sense of stability.</p><p>Helpful strategies include⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#acute-longer-term-outcomes-depressed-outpatients-requiring-one-several\" data-reference-link=\"\" aria-label=\"Reference 5: Rush, A. J., Trivedi, M. H., Wisniewski, S. R., et al. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report. American Journal of Psychiatry, 163(11), 1905–1917. PsychiatryOnline. Accessed May 23 2025.\" data-reference-number=\"5\">[5]</a><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#persistent-depressive-disorder-dysthymic-disorder\" data-reference-link=\"\" aria-label=\"Reference 7: National Institute of Mental Health. (2022). Persistent depressive disorder (dysthymic disorder). National Institute of Mental Health. Accessed October 10 2026.\" data-reference-number=\"7\">[7]</a></sup>: </p><ul class=\"wp-block-list\">\n<li><strong><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/mindfulness-therapy\">Mindfulness-based practices</a>:</strong> Meditation, yoga, art therapy, and other mindfulness practices improve emotional awareness and reduce rumination.</li>\n<li><strong>Outdoor activity and natural light:</strong> Fresh air and sunlight improve moods and regulate circadian rhythms. </li>\n<li><strong>Balanced nutrition:</strong> It is important to eat fruits, vegetables, and whole foods while limiting sugar, caffeine, and alcohol.</li>\n<li><strong>Build routines:</strong> Plan for daily movement, structured sleep, or achievable goals to combat inactivity and disengagement.</li>\n</ul><p>These habits don’t replace professional care but can enhance its effectiveness and support greater resilience over time.</p><h2 id=\"building-a-personal-support-network\">Building a Personal Support Network</h2><p>Clinical treatment is essential for managing persistent depression, but <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/social-health\">social support</a> also plays a decisive role in recovery. A strong network can buffer the impact of stress, increase treatment adherence, and provide a sense of belonging, all of which people with PDD often struggle to maintain⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#depression-diagnosis-treatment\" data-reference-link=\"\" aria-label=\"Reference 4: Mayo Clinic. (2023). Depression: Diagnosis and treatment. Mayo Clinic. Accessed October 10 2026.\" data-reference-number=\"4\">[4]</a><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#depression-source\" data-reference-link=\"\" aria-label=\"Reference 8: World Health Organization. (2021). Depression. World Health Organization. Accessed October 10 2026.\" data-reference-number=\"8\">[8]</a></sup>.</p><p>Support doesn’t have to come from a large circle. A few trusted connections can offer the most meaningful impact, whether friends, family members, coworkers, or community members.</p><p>Key elements of a healthy support network include:</p><ul class=\"wp-block-list\">\n<li><strong>Emotional support:</strong> People who listen without judgment and validate the experience of chronic depression </li>\n<li><strong>Practical assistance:</strong> Those who help with day-to-day needs or check in consistently</li>\n<li><strong>Encouragement:</strong> Friends, loved ones, and healthcare providers who help maintain motivation for treatment, self-care, or positive routines</li>\n</ul><p>Support looks different for everyone, taking many forms depending on individual needs and comfort levels. It might come from close family, a trusted friend, a community group, or even a therapist.</p><h3 id=\"interpersonal-relationships\">Interpersonal Relationships</h3><p>Although it can be challenging to reach out, especially during periods of low energy or motivation, supportive relationships often make recovery more sustainable. That said, an individual may need to reshape relationships or set boundaries to <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/the-importance-of-feeling-safe\">promote emotional safety</a>. In the context of persistent depression, feeling seen, understood, and connected is as important as medication or therapy in encouraging long-term resilience.</p><h3 id=\"peer-support-groups\">Peer Support Groups</h3><p><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/support-groups\">Peer support groups</a>, whether in-person or virtual, can also be beneficial. These spaces provide opportunities to connect with others who understand the challenges of living with persistent depression. Researchers have found that group settings reduce isolation, increase hope, and assist the development of healthy coping skills⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#depression-source\" data-reference-link=\"\" aria-label=\"Reference 8: World Health Organization. (2021). Depression. World Health Organization. Accessed October 10 2026.\" data-reference-number=\"8\">[8]</a></sup>.</p><h3 id=\"mental-health-professionals\">Mental Health Professionals</h3><p><a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/people\">Mental health professionals</a> can help clients identify gaps in their support systems so they can build or rebuild connections over time. Therapists may incorporate interpersonal goals into treatment plans, especially when loneliness or strained relationships contribute to depressive symptoms.</p><h2 id=\"knowing-when-to-seek-immediate-help\">Knowing When to Seek Immediate Help</h2><p>In some cases, persistent depressive disorder can escalate into <a class=\"article-inline-link\" href=\"https://www.mentalhealth.com/library/major-depressive-disorder\">major depressive episodes</a>⁠<sup class=\"citation-group\"><a class=\"article-citation\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#persistent-depressive-disorder-dysthymic-disorder\" data-reference-link=\"\" aria-label=\"Reference 7: National Institute of Mental Health. (2022). Persistent depressive disorder (dysthymic disorder). National Institute of Mental Health. Accessed October 10 2026.\" data-reference-number=\"7\">[7]</a></sup>. A major depressive episode is marked by a cluster of more severe symptoms, such as overwhelming sadness, complete disinterest in once-routine activities, and extreme fatigue, that persist for at least two weeks and significantly impair a person’s ability to function. Unlike the more chronic but lower-grade symptoms of persistent depression, these episodes tend to be more intense, acute, and emotionally debilitating.</p><p>Warning signs that depression may be worsening include a deepening sense of hopelessness and emerging thoughts of self-harm. Individuals may also experience notable disruptions to sleep and appetite, retreat from everyday responsibilities and social interactions, and neglect personal care. Emotional numbness or suicidal thoughts may signal a critical need for intervention.</p><p>When symptoms intensify, prompt action is essential. Accessing support from a licensed mental health provider or a crisis line can help ensure immediate safety and connect individuals to appropriate care.</p><p>In addition to emergency services or crisis lines, involving a trusted support person or mental health provider early on can be essential. Developing a safety plan in advance that includes warning signs, emergency contacts, and coping strategies may reduce risk and help ensure a faster, more effective response during periods of worsening symptoms.</p><h2 id=\"staying-the-course-for-long-term-recovery\">Staying the Course for Long-Term Recovery</h2><p>Managing persistent depression isn’t about eliminating every low moment; it’s about finding steadiness, building resilience, and creating a life that feels more manageable and meaningful. Recovery rarely happens quickly, but every bit of forward movement matters.</p><p>Depression recovery becomes more sustainable when treatment is consistent, healthy habits are nurtured, and <a href=\"https://www.mentalhealth.com/library/relationships-support\" class=\"article-inline-link\" data-context-link=\"358\">supportive relationships</a> are part of daily life. Even small improvements, such as more energy, a clearer thought, or a renewed connection, can signal meaningful change.</p><p>Whether someone is living with PDD or offering care and encouragement to a loved one, the path forward doesn’t require perfection. What matters most is movement in the right direction, one steady, supported step at a time.</p></article><div class=\"article-endmatter\"><section class=\"article-sources\" data-reference-list=\"\" data-reference-style=\"author-date-title-source\" data-source-references=\"\" id=\"references\"><h2 id=\"references-2\">References</h2><ol><li id=\"depression\" value=\"1\" data-reference-number=\"1\" data-reference-format=\"393\">National Institute of Mental Health. (n.d.). <em class=\"reference-title\">Depression.</em> U.S. Department of Health and Human Services. <a href=\"https://www.nimh.nih.gov/health/publications/depression?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">National Institute of Mental Health</a>. Accessed October 10 2026.</li><li id=\"epidemiology-dysthymia-five-communities-rates-risks-comorbidity-treatment\" value=\"2\" data-reference-number=\"2\" data-reference-format=\"393\">Weissman, M. M., Leaf, P. J., Holzer, C. E., Myers, J. K., &amp; Tischler, G. L. (1988). <em class=\"reference-title\">The epidemiology of dysthymia in five communities: Rates, risks, comorbidity, and treatment.</em> The American Journal of Psychiatry, 145(7), 815–819. <a href=\"https://psychiatryonline.org/doi/10.1176/ajp.145.7.815?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">PsychiatryOnline</a>. Accessed May 23 2025.</li><li id=\"persistent-depressive-disorder\" value=\"3\" data-reference-number=\"3\" data-reference-format=\"393\">Mayo Clinic. (2023). <em class=\"reference-title\">Persistent depressive disorder.</em> <a href=\"https://www.mayoclinic.org/diseases-conditions/persistent-depressive-disorder/symptoms-causes/syc-20350929?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">Mayo Clinic</a>. Accessed October 10 2026.</li><li id=\"depression-diagnosis-treatment\" value=\"4\" data-reference-number=\"4\" data-reference-format=\"393\">Mayo Clinic. (2023). <em class=\"reference-title\">Depression: Diagnosis and treatment.</em> <a href=\"https://www.mayoclinic.org/diseases-conditions/depression/diagnosis-treatment/drc-20356013?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">Mayo Clinic</a>. Accessed October 10 2026.</li><li id=\"acute-longer-term-outcomes-depressed-outpatients-requiring-one-several\" value=\"5\" data-reference-number=\"5\" data-reference-format=\"393\">Rush, A. J., Trivedi, M. H., Wisniewski, S. R., et al. (2006). <em class=\"reference-title\">Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report.</em> American Journal of Psychiatry, 163(11), 1905–1917. <a href=\"https://psychiatryonline.org/doi/10.1176/ajp.2006.163.11.1905?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">PsychiatryOnline</a>. Accessed May 23 2025.</li><li id=\"randomized-trial-behavioral-activation-cognitive-therapy-antidepressant-medication-acute\" value=\"6\" data-reference-number=\"6\" data-reference-format=\"393\">Dimidjian, S., Hollon, S. D., Dobson, K. S., et al. (2006). <em class=\"reference-title\">Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression.</em> Journal of Consulting and Clinical Psychology, 74(4), 658–670. <a href=\"https://psycnet.apa.org:443/doiLanding?doi=10.1037%2F0022-006X.74.4.658&amp;utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">psycnet.apa.org:443</a>. Accessed May 23 2025.</li><li id=\"persistent-depressive-disorder-dysthymic-disorder\" value=\"7\" data-reference-number=\"7\" data-reference-format=\"393\">National Institute of Mental Health. (2022). <em class=\"reference-title\">Persistent depressive disorder (dysthymic disorder).</em> <a href=\"https://www.nimh.nih.gov/health/statistics/persistent-depressive-disorder-dysthymic-disorder?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">National Institute of Mental Health</a>. Accessed October 10 2026.</li><li id=\"depression-source\" value=\"8\" data-reference-number=\"8\" data-reference-format=\"393\">World Health Organization. (2021). <em class=\"reference-title\">Depression.</em> <a href=\"https://www.who.int/news-room/fact-sheets/detail/depression?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-managing-persistent-depression&amp;utm_source=mentalhealth.com\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" class=\"reference-source\">World Health Organization</a>. Accessed October 10 2026.</li></ol></section><section class=\"article-medical article-panel\"><h2 id=\"medical-content\">Medical Content</h2><p><a href=\"https://www.mentalhealth.com/clinical-affairs\">The Clinical Affairs Team</a> at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the <a href=\"https://www.mentalhealth.com/publishing/editorial-policy\">Editorial Policy</a>.</p></section><section class=\"article-about article-panel\"><h2 id=\"about-mentalhealth-com\">About MentalHealth.com</h2><p>MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.</p><div class=\"article-contributors\"><section class=\"article-bio\"><a href=\"https://www.mentalhealth.com/people/sue-collier\" class=\"card-identity-photo\" aria-label=\"Sue Collier, B.A.\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"https://www.mentalhealth.com/assets/optimized/a7cb37e41d2dd524db4b3936.jpg\" width=\"64\" decoding=\"async\"></a><div><p class=\"article-bio-role\">Author</p><h3 id=\"sue-collier\"><a href=\"https://www.mentalhealth.com/people/sue-collier\">Sue Collier, B.A.</a></h3><p class=\"article-bio-credentials\">BA</p><p>Sue Collier is a seasoned editor and content writer with decades of experience across healthcare, dental, legal, education, and technology sectors.</p><dl><div><dt>Published</dt><dd><time datetime=\"2025-06-05T09:33:37Z\">June 5, 2025</time></dd></div><div><dt>Updated</dt><dd><time datetime=\"2026-05-12T12:21:51Z\">May 12, 2026</time></dd></div></dl></div></section><section class=\"article-bio\"><a href=\"https://www.mentalhealth.com/people/shivani-kharod\" class=\"card-identity-photo\" aria-label=\"Shivani Kharod, Ph.D.\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"https://www.mentalhealth.com/assets/optimized/d298e1ab0221c766e22a9fce.jpg\" width=\"64\" decoding=\"async\"></a><div><p class=\"article-bio-role\">Medical Reviewer</p><h3 id=\"shivani-kharod-ph-d\"><a href=\"https://www.mentalhealth.com/people/shivani-kharod\">Shivani Kharod, Ph.D.</a></h3><p class=\"article-bio-credentials\">Ph.D.</p><p>Shivani Kharod, Ph.D. is a medical reviewer with over 10 years of experience in delivering scientifically accurate health content.</p><dl><div><dt>Reviewed</dt><dd><time datetime=\"2025-06-05\">June 5, 2025</time></dd></div></dl></div></section></div></section><section aria-label=\"Related community\" class=\"article-topic-community article-topic-community-end\"><a href=\"https://www.mentalhealth.com/community/depression\" class=\"card-identity-photo\" aria-label=\"Depression\"><img alt=\"\" class=\"topic-community-banner\" height=\"675\" loading=\"lazy\" src=\"https://www.mentalhealth.com/assets/optimized/91211a50ddeaa7fa8b3e0af9.webp\" width=\"1200\" decoding=\"async\" srcset=\"/assets/responsive/a4f14d631a3c579a02f683c8.webp 800w, /assets/optimized/91211a50ddeaa7fa8b3e0af9.webp 1200w\" sizes=\"(min-width: 961px) 236px, calc(100vw - 80px)\"></a><p class=\"topic-community-label\">Related community</p><h2><a href=\"https://www.mentalhealth.com/community/depression\">Depression</a></h2><p>A place for understanding depression and sharing perspectives on its impact on daily life.</p></section></div></div><aside aria-label=\"Article navigation and related information\" class=\"article-sidebar\" data-bounded-rail=\"\" tabindex=\"0\"><details class=\"article-contents\" data-expanded=\"false\" data-scrolled-past=\"false\" data-section-preview=\"3\" open=\"\"><summary><strong>Table of contents</strong><span aria-hidden=\"true\"></span><small data-current-section=\"\">Choose a section</small></summary><nav aria-label=\"Article contents\"><ol id=\"article-section-list\"><li><a aria-label=\"What Makes Persistent Depression Different?\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#what-makes-persistent-depression-different\" title=\"What Makes Persistent Depression Different?\">What Makes Persistent Depression Different?</a></li><li><a aria-label=\"The Signs of Persistent Depression\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#the-signs-of-persistent-depression\" title=\"The Signs of Persistent Depression\">The Signs of Persistent Depression</a></li><li><a aria-label=\"Risk Factors of Persistent Depression\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#risk-factors-of-persistent-depression\" title=\"Risk Factors of Persistent Depression\">Risk Factors of Persistent Depression</a></li><li><a aria-label=\"Diagnosing Persistent Depression\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#diagnosing-persistent-depression\" title=\"Diagnosing Persistent Depression\">Diagnosing Persistent Depression</a></li><li><a aria-label=\"Treatment Approaches for Managing PDD\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#treatment-approaches-for-managing-pdd\" title=\"Treatment Approaches for Managing PDD\">Treatment Approaches for Managing PDD</a></li><li><a aria-label=\"Daily Habits That Support Recovery\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#daily-habits-that-support-recovery\" title=\"Daily Habits That Support Recovery\">Daily Habits That Support Recovery</a></li><li><a aria-label=\"Building a Personal Support Network\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#building-a-personal-support-network\" title=\"Building a Personal Support Network\">Building a Personal Support Network</a></li><li><a aria-label=\"Knowing When to Seek Immediate Help\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#knowing-when-to-seek-immediate-help\" title=\"Knowing When to Seek Immediate Help\">Knowing When to Seek Immediate Help</a></li><li><a aria-label=\"Staying the Course for Long-Term Recovery\" href=\"https://www.mentalhealth.com/library/managing-persistent-depression#staying-the-course-for-long-term-recovery\" title=\"Staying the Course for Long-Term Recovery\">Staying the Course for Long-Term Recovery</a></li></ol><button aria-controls=\"article-section-list\" aria-expanded=\"false\" class=\"article-sections-toggle\" data-sections-toggle=\"\" type=\"button\">View more</button></nav></details></aside></div></div></div>","text":"Home Library Depression Managing Persistent Depression Managing Persistent Depression Written by Sue Collier, B.A.Medically reviewed by Shivani Kharod, Ph.D. Published on June 5, 2025 · Updated on May 12, 2026 People living with persistent depressive disorder (PDD) face ongoing depressive symptoms that may seem milder than those of major depression. It can drain energy, dull joy, and make even simple tasks feel overwhelming. It often shows up as chronic sadness, low motivation, and a lack of interest in things that once mattered. Fortunately, several proven strategies can help manage persistent depression and improve daily functioning. Key takeaways Persistent depressive disorder involves depressive symptoms lasting at least two years in adults or one year in young people. Its long duration can drain energy and enjoyment even when a person continues meeting daily responsibilities. Consistent treatment, manageable routines, and supportive relationships can promote gradual improvement and sustained recovery. What Makes Persistent Depression Different? Persistent depressive disorder is a chronic form of depression lasting at least two years in adults or one year in children and adolescents⁠[1]. Also known as dysthymia, its symptoms are less intense than those of major depressive disorder, though they last longer and are more ingrained in daily life. People with PDD often describe life as a continuous emotional struggle. They may maintain jobs, care for family, and fulfill responsibilities, yet feel depleted or numb internally. Symptoms develop slowly and linger, often mistaken for personality traits or life circumstances, making early recognition and intervention especially important. Subject matter expert Simone Hoermann Ph.D. Personality disorders, anxiety, and depression View profile The Signs of Persistent Depression Symptoms of persistent depressive disorder (PDD), also known as dysthymia, often emerge gradually and can become so ingrained in daily life that they go unnoticed. Over time, these symptoms may become intertwined with a person’s self-perception, making them particularly difficult to recognize and diagnose. Still, there are patterns, both behavioral and emotional, that can signal the presence of PDD. These signs may not be dramatic, but they often interfere with relationships, responsibilities, and overall well-being. Behavioral changes may include overeating or undereating and sleeping too much or too little. Some people might experience trouble focusing or making decisions, constant fatigue or low energy, delays completing tasks, or reduced work quality. Another sign is withdrawing from social situations or relationships. Emotional indicators of persistent depression often reveal themselves in subtle but disruptive ways. Individuals may experience a persistent sense of low self-worth or ongoing self-doubt, along with feelings of sadness, emptiness, or hopelessness that linger over time. Guilt can arise frequently, sometimes triggered by minor concerns, and this emotional weight is often paired with apathy toward activities that once felt meaningful. Heightened sensitivity or irritability may also emerge, making it harder to cope with everyday stressors or social interactions. These symptoms can persist for years and often overlap with other conditions. Only about 25%-30% of people with PDD experience it in isolation, without other psychiatric disorders⁠[2]. Risk Factors of Persistent Depression The exact cause of PDD remains unclear, but research suggests multiple contributing factors. According to the Mayo Clinic, persistent depression may stem from a mix of biological, genetic, and psychosocial influences, including⁠[3]: Neurochemical imbalances: Disruptions in neurotransmitters can impair emotional regulation. Genetics: People with a family history of mood disorders are at higher risk of persistent depression. Chronic stress or trauma: Prolonged life challenges, such as loss or instability, may trigger depressive symptoms. Personality traits: People with low self-esteem or a pessimistic outlook may be more vulnerable to PDD. While these factors don’t determine whether someone will develop PDD, they help explain who might be more susceptible and why symptoms often persist over time. Diagnosing Persistent Depression Persistent depression often co-occurs with anxiety or physical illness, and accurate diagnosis requires a comprehensive evaluation. Mental health professionals use psychological assessments, medical and psychiatric histories, and sometimes lab tests to rule out physical causes of symptoms. A diagnosis of PDD depends heavily on symptom duration. In general, PPD lasts at least two years in adults and at least one year in children and adolescents⁠[3]. Since symptoms mimic other conditions, professionals strongly advise against self-diagnosis. Therefore, it’s important that individuals seek a professional assessment as early diagnosis can significantly improve outcomes. Treatment Approaches for Managing PDD Once diagnosed, effective management of PDD usually involves a combination of medication, psychotherapy, and lifestyle changes⁠[4]. Given the chronic nature of the disorder, the treatment approach should be personalized to match each individual's unique needs, Medications may include: SSRIs: Selective serotonin reuptake inhibitors (SSRIs) such as sertraline or fluoxetine SNRIs: Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine Atypical antidepressants: Medications such as bupropion If initial treatment does not provide complete relief, clinicians may adjust the dosage or introduce additional medications⁠[5]. Considering antidepressants typically take several weeks to become effective, regular monitoring is essential to evaluate progress and manage potential side effects. Psychotherapy options include⁠[6]: Cognitive-Behavioral Therapy (CBT): Cognitive behavioral therapy (CBT) targets negative thinking patterns. Interpersonal Therapy (IPT): IPT focuses on relationship dynamics. Psychodynamic therapy: Psychodynamic therapy addresses unconscious emotional patterns. Behavioral activation: Behavioral activation includes re-engagement with enjoyable or meaningful activities. While medication and therapy are helpful on their own, evidence suggests that combining therapy with medication is especially effective for chronic or treatment-resistant depression. Find support that fits you Explore people and care options near you. Find careDaily Habits That Support Recovery In addition to clinical treatment, daily habits and lifestyle adjustments play a vital role in managing persistent depression. Long-term recovery is often supported not just by what happens in the therapist’s office or with medication but by small, consistent efforts made throughout everyday life. Establishing structure and routine can reduce stress and help regulate mood. When low energy or motivation, simple, repeatable actions, such as eating regular meals or maintaining a consistent sleep schedule, can create a sense of stability. Helpful strategies include⁠[5][7]: Mindfulness-based practices: Meditation, yoga, art therapy, and other mindfulness practices improve emotional awareness and reduce rumination. Outdoor activity and natural light: Fresh air and sunlight improve moods and regulate circadian rhythms. Balanced nutrition: It is important to eat fruits, vegetables, and whole foods while limiting sugar, caffeine, and alcohol. Build routines: Plan for daily movement, structured sleep, or achievable goals to combat inactivity and disengagement. These habits don’t replace professional care but can enhance its effectiveness and support greater resilience over time. Building a Personal Support Network Clinical treatment is essential for managing persistent depression, but social support also plays a decisive role in recovery. A strong network can buffer the impact of stress, increase treatment adherence, and provide a sense of belonging, all of which people with PDD often struggle to maintain⁠[4][8]. Support doesn’t have to come from a large circle. A few trusted connections can offer the most meaningful impact, whether friends, family members, coworkers, or community members. Key elements of a healthy support network include: Emotional support: People who listen without judgment and validate the experience of chronic depression Practical assistance: Those who help with day-to-day needs or check in consistently Encouragement: Friends, loved ones, and healthcare providers who help maintain motivation for treatment, self-care, or positive routines Support looks different for everyone, taking many forms depending on individual needs and comfort levels. It might come from close family, a trusted friend, a community group, or even a therapist. Interpersonal Relationships Although it can be challenging to reach out, especially during periods of low energy or motivation, supportive relationships often make recovery more sustainable. That said, an individual may need to reshape relationships or set boundaries to promote emotional safety. In the context of persistent depression, feeling seen, understood, and connected is as important as medication or therapy in encouraging long-term resilience. Peer Support Groups Peer support groups, whether in-person or virtual, can also be beneficial. These spaces provide opportunities to connect with others who understand the challenges of living with persistent depression. Researchers have found that group settings reduce isolation, increase hope, and assist the development of healthy coping skills⁠[8]. Mental Health Professionals Mental health professionals can help clients identify gaps in their support systems so they can build or rebuild connections over time. Therapists may incorporate interpersonal goals into treatment plans, especially when loneliness or strained relationships contribute to depressive symptoms. Knowing When to Seek Immediate Help In some cases, persistent depressive disorder can escalate into major depressive episodes⁠[7]. A major depressive episode is marked by a cluster of more severe symptoms, such as overwhelming sadness, complete disinterest in once-routine activities, and extreme fatigue, that persist for at least two weeks and significantly impair a person’s ability to function. Unlike the more chronic but lower-grade symptoms of persistent depression, these episodes tend to be more intense, acute, and emotionally debilitating. Warning signs that depression may be worsening include a deepening sense of hopelessness and emerging thoughts of self-harm. Individuals may also experience notable disruptions to sleep and appetite, retreat from everyday responsibilities and social interactions, and neglect personal care. Emotional numbness or suicidal thoughts may signal a critical need for intervention. When symptoms intensify, prompt action is essential. Accessing support from a licensed mental health provider or a crisis line can help ensure immediate safety and connect individuals to appropriate care. In addition to emergency services or crisis lines, involving a trusted support person or mental health provider early on can be essential. Developing a safety plan in advance that includes warning signs, emergency contacts, and coping strategies may reduce risk and help ensure a faster, more effective response during periods of worsening symptoms. Staying the Course for Long-Term Recovery Managing persistent depression isn’t about eliminating every low moment; it’s about finding steadiness, building resilience, and creating a life that feels more manageable and meaningful. Recovery rarely happens quickly, but every bit of forward movement matters. Depression recovery becomes more sustainable when treatment is consistent, healthy habits are nurtured, and supportive relationships are part of daily life. Even small improvements, such as more energy, a clearer thought, or a renewed connection, can signal meaningful change. Whether someone is living with PDD or offering care and encouragement to a loved one, the path forward doesn’t require perfection. What matters most is movement in the right direction, one steady, supported step at a time. References National Institute of Mental Health. (n.d.). Depression. U.S. Department of Health and Human Services. National Institute of Mental Health. Accessed October 10 2026. Weissman, M. M., Leaf, P. J., Holzer, C. E., Myers, J. K., & Tischler, G. L. (1988). The epidemiology of dysthymia in five communities: Rates, risks, comorbidity, and treatment. The American Journal of Psychiatry, 145(7), 815–819. PsychiatryOnline. Accessed May 23 2025. Mayo Clinic. (2023). Persistent depressive disorder. Mayo Clinic. Accessed October 10 2026. Mayo Clinic. (2023). Depression: Diagnosis and treatment. Mayo Clinic. Accessed October 10 2026. Rush, A. J., Trivedi, M. H., Wisniewski, S. R., et al. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report. American Journal of Psychiatry, 163(11), 1905–1917. PsychiatryOnline. Accessed May 23 2025. Dimidjian, S., Hollon, S. D., Dobson, K. S., et al. (2006). Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. Journal of Consulting and Clinical Psychology, 74(4), 658–670. psycnet.apa.org:443. Accessed May 23 2025. National Institute of Mental Health. (2022). Persistent depressive disorder (dysthymic disorder). National Institute of Mental Health. Accessed October 10 2026. World Health Organization. (2021). Depression. World Health Organization. Accessed October 10 2026. Medical Content The Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy. About MentalHealth.com MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life. Author Sue Collier, B.A. BA Sue Collier is a seasoned editor and content writer with decades of experience across healthcare, dental, legal, education, and technology sectors. Published June 5, 2025 Updated May 12, 2026 Medical Reviewer Shivani Kharod, Ph.D. Ph.D. Shivani Kharod, Ph.D. is a medical reviewer with over 10 years of experience in delivering scientifically accurate health content. Reviewed June 5, 2025 Related community Depression A place for understanding depression and sharing perspectives on its impact on daily life. Table of contentsChoose a section What Makes Persistent Depression Different? The Signs of Persistent Depression Risk Factors of Persistent Depression Diagnosing Persistent Depression Treatment Approaches for Managing PDD Daily Habits That Support Recovery Building a Personal Support Network Knowing When to Seek Immediate Help Staying the Course for Long-Term Recovery View more","wordCount":2132},"schema":{"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://www.mentalhealth.com/#organization","name":"MentalHealth.com","url":"https://www.mentalhealth.com/","publishingPrinciples":"https://www.mentalhealth.com/publishing/editorial-policy"},{"@type":"WebSite","@id":"https://www.mentalhealth.com/#website","url":"https://www.mentalhealth.com/","name":"MentalHealth.com","inLanguage":"en-US","publisher":{"@id":"https://www.mentalhealth.com/#organization"}},{"@type":"BreadcrumbList","@id":"https://www.mentalhealth.com/library/managing-persistent-depression#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.mentalhealth.com/"},{"@type":"ListItem","position":2,"name":"Library","item":"https://www.mentalhealth.com/library"},{"@type":"ListItem","position":3,"name":"Depression","item":"https://www.mentalhealth.com/library/depression"},{"@type":"ListItem","position":4,"name":"Managing Persistent Depression","item":"https://www.mentalhealth.com/library/managing-persistent-depression"}]},{"@type":"ImageObject","@id":"https://www.mentalhealth.com/library/managing-persistent-depression#primaryimage","url":"https://www.mentalhealth.com/assets/optimized/be4f543e0654ec8a3a09f898.webp","contentUrl":"https://www.mentalhealth.com/assets/optimized/be4f543e0654ec8a3a09f898.webp","width":1200,"height":674,"encodingFormat":"image/webp","caption":"A person sits with their hands resting together in their lap."},{"@type":"Person","@id":"https://www.mentalhealth.com/people/sue-collier#person","name":"Sue Collier","url":"https://www.mentalhealth.com/people/sue-collier","jobTitle":"BA","image":"https://www.mentalhealth.com/assets/optimized/a7cb37e41d2dd524db4b3936.jpg","sameAs":["https://www.linkedin.com/in/suecollier/"],"memberOf":[{"@id":"https://www.mentalhealth.com/publishing#department"}]},{"@type":"Person","@id":"https://www.mentalhealth.com/people/shivani-kharod#person","name":"Shivani Kharod, Ph.D.","url":"https://www.mentalhealth.com/people/shivani-kharod","jobTitle":"Ph.D.","image":"https://www.mentalhealth.com/assets/optimized/d298e1ab0221c766e22a9fce.jpg","sameAs":["https://www.linkedin.com/in/shivanikharod"],"memberOf":[{"@id":"https://www.mentalhealth.com/clinical-affairs#department"}]},{"@type":"Article","@id":"https://www.mentalhealth.com/library/managing-persistent-depression#article","url":"https://www.mentalhealth.com/library/managing-persistent-depression","headline":"Managing Persistent Depression","description":"Learn about persistent depressive disorder, its symptoms, treatment, and proven tools for recovery, support, and self-care.","wordCount":1656,"mainEntityOfPage":{"@id":"https://www.mentalhealth.com/library/managing-persistent-depression#webpage"},"publisher":{"@id":"https://www.mentalhealth.com/#organization"},"articleSection":"Depression","citation":[{"@type":"CreativeWork","name":"National Institute of Mental Health. 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